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Hauptverfasser: Monti, Edoardo, Yatsyshin, Peter, Gkagkas, Konstantinos, Duncan, Andrew B.
Format: Preprint
Veröffentlicht: 2025
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2512.23840
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author Monti, Edoardo
Yatsyshin, Peter
Gkagkas, Konstantinos
Duncan, Andrew B.
author_facet Monti, Edoardo
Yatsyshin, Peter
Gkagkas, Konstantinos
Duncan, Andrew B.
contents Predicting interfacial thermodynamics across molecular and continuum scales remains a central challenge in computational science. Classical density functional theory (cDFT) provides a first-principles route to connect microscopic interactions with macroscopic observables, but its predictive accuracy depends on approximate free-energy functionals that are difficult to generalize. Here we introduce a physics-informed learning framework that augments cDFT with neural corrections trained directly against molecular-dynamics data through adjoint optimization. Rather than replacing the theory with a black-box surrogate, we embed compact neural networks within the Helmholtz free-energy functional, learning local and nonlocal corrections that preserve thermodynamic consistency while capturing missing correlations. Applied to Lennard-Jones fluids, the resulting augmented excess free-energy functional quantitatively reproduces equilibrium density profiles, coexistence curves, and surface tensions across a broad temperature range, and accurately predicts contact angles and droplet shapes far beyond the training regime. This approach combines the interpretability of statistical mechanics with the adaptability of modern machine learning, establishing a general route to learned thermodynamic functionals that bridge molecular simulations and continuum-scale models.
format Preprint
id arxiv_https___arxiv_org_abs_2512_23840
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Learning Density Functionals to Bridge Particle and Continuum Scales
Monti, Edoardo
Yatsyshin, Peter
Gkagkas, Konstantinos
Duncan, Andrew B.
Computational Physics
Statistical Mechanics
Predicting interfacial thermodynamics across molecular and continuum scales remains a central challenge in computational science. Classical density functional theory (cDFT) provides a first-principles route to connect microscopic interactions with macroscopic observables, but its predictive accuracy depends on approximate free-energy functionals that are difficult to generalize. Here we introduce a physics-informed learning framework that augments cDFT with neural corrections trained directly against molecular-dynamics data through adjoint optimization. Rather than replacing the theory with a black-box surrogate, we embed compact neural networks within the Helmholtz free-energy functional, learning local and nonlocal corrections that preserve thermodynamic consistency while capturing missing correlations. Applied to Lennard-Jones fluids, the resulting augmented excess free-energy functional quantitatively reproduces equilibrium density profiles, coexistence curves, and surface tensions across a broad temperature range, and accurately predicts contact angles and droplet shapes far beyond the training regime. This approach combines the interpretability of statistical mechanics with the adaptability of modern machine learning, establishing a general route to learned thermodynamic functionals that bridge molecular simulations and continuum-scale models.
title Learning Density Functionals to Bridge Particle and Continuum Scales
topic Computational Physics
Statistical Mechanics
url https://arxiv.org/abs/2512.23840