Local shear signals propagate to suppress local cellular motion in stiff epithelia

Fuente: arXiv

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Nahum, Shahar, Elkabetz, Adi Y., Elbaz, Matan, Daraf, Liav, Lavi, Yael, Atia, Lior
Format:	Preprint
Publié:	2025
Sujets:	Biological Physics
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

A self-organized compression network arrests epithelial proliferation
par: Daraf, Liav, et autres
Publié: (2025)

Multiscale order, flocking and phenotypic hysteresis in the cellular Potts model of epithelia
par: Bakker, Calvin C., et autres
Publié: (2026)

Geometry of T1 transitions in epithelia
par: Haas, Pierre A.
Publié: (2025)

Hydrodynamics and multiscale order in confluent epithelia
par: Armengol-Collado, Josep-Maria, et autres
Publié: (2022)

Direct and retrograde signal propagation in unidirectionally coupled Wilson-Cowan oscillators
par: Elisha, Guy, et autres
Publié: (2024)

Transcription-induced active forces suppress chromatin motion
par: Shin, Sucheol, et autres
Publié: (2022)

Collective migration and topological phase transitions in confluent epithelia
par: Puggioni, Leonardo, et autres
Publié: (2025)

Thickness of epithelia on wavy substrates: measurements and continuous models
par: Harmand, Nicolas, et autres
Publié: (2025)

Transverse contributions to the longitudinal stiffness of the human foot
par: Yawar, Ali, et autres
Publié: (2017)

Glassy dynamics in active epithelia emerge from an interplay of mechanochemical feedback and crowding
par: Muthukrishnan, Sindhu, et autres
Publié: (2025)

The miscalibration of the honeybee odometer
par: Luebbert, Laura, et autres
Publié: (2024)

Co-regulation of multi-cellular swirling by individual cellular chirality and boundaries
par: Li, Xi, et autres
Publié: (2023)

A multi-physics approach to probing plant responses: From calcium signaling to thigmonastic motion
par: Gennis, Sabrina, et autres
Publié: (2025)

Morphological instability at topological defects in a three-dimensional vertex model for spherical epithelia
par: Drozdowski, Oliver M., et autres
Publié: (2024)

Collective multicellular patterns arising from cadherin-linked cytoskeletal domains
par: Du, XinXin, et autres
Publié: (2025)

Necking of epithelial tissues with cellular topological transition
par: He, Yuan, et autres
Publié: (2025)

Messenger size optimality in cellular communications
par: Tirandaz, Arash, et autres
Publié: (2024)

A self-organised liquid reaction container for cellular memory
par: Mukherjee, Sukanta, et autres
Publié: (2024)

Separation of ionic timescales explains dynamics of cellular volume regulation
par: Adar, Ram M.
Publié: (2024)

Nonlinear spontaneous flow instability in active nematics
par: Lavi, Ido, et autres
Publié: (2024)

Imaging protein interactions in vivo with sub-cellular resolution
par: Raicu, Valerica, et autres
Publié: (2008)

Information thermodynamics of cellular ion pumps
par: Jiménez-Paz, Julian D., et autres
Publié: (2025)

Allosteric propagation of curvature along filament
par: Sekimoto, Ken
Publié: (2024)

Substrate stiffness governs dynamics and self-organization of nascent biofilms
par: Rani, Garima, et autres
Publié: (2025)

Cellular-scale mechanism of cell crawling responding to substrate stiffness
par: Nakamura, Sohei, et autres
Publié: (2026)

Quantifying cellular autonomy in multi-cue environments
par: Gonzalez, Louis, et autres
Publié: (2024)

Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications
par: Grasso, Giuliana, et autres
Publié: (2024)

Technical recommendation on multiplex MR elastography for tomographic mapping of abdominal stiffness with a focus on the pancreas and pancreatic ductal adenocarcinoma
par: Schattenfroh, Jakob, et autres
Publié: (2025)

Phase changes of the flow rate in the vertebral artery caused by debranching thoracic endovascular aortic repair: effects of flow path and local vessel stiffness on vertebral arterial pulsation
par: Takeishia, Naoki, et autres
Publié: (2024)

Towards predicting shear-banding instabilities in lipid monolayers
par: Carotenuto, A. R., et autres
Publié: (2024)

Evolutionary origin of the bipartite architecture of dissipative cellular networks
par: Shi, Bowen, et autres
Publié: (2024)

The virial theorem and the Price equation
par: Felce, Catherine, et autres
Publié: (2023)

Lagrangian for Navier-Stokes equations of motion: SDPD approach
par: Kornilova, Tatyana, et autres
Publié: (2026)

From modelling to understanding: the signals in nerves
par: Engelbrecht, Jüri, et autres
Publié: (2024)

Breakdown of Boltzmann-type Models for the Alignment of Self-propelled Rods
par: Murphy, Patrick, et autres
Publié: (2023)

Data-driven classification of individual cells by their non-Markovian motion
par: Klimek, Anton, et autres
Publié: (2023)

Near-infrared fluorescent nanoprobes for irreversibility in nonequilibrium actomyosin networks
par: Hendler-Neumark, Adi, et autres
Publié: (2025)

A quantum picture of light-suppressed photosynthetic charge transfer
par: Yang, Guang, et autres
Publié: (2024)

Synthetic frequency-controlled gene circuits unlock expanded cellular states
par: Zhang, Rongrong, et autres
Publié: (2024)

Poissonian cellular Potts models reveal nonequilibrium kinetics of cell sorting
par: Belousov, Roman, et autres
Publié: (2023)

if (filemtime($filename) + $maxlifetime < time()) { unlink($filename); $count++; } } return $count; } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ protected function saveSession($sessId, $data): bool { $sessFile = $this->path . '/sess_' . $sessId; if ($handle = fopen($sessFile, 'w')) { $return = false; // Lock the file for exclusive access to avoid issues with multiple // processes writing session simultaneously: if (flock($handle, LOCK_EX)) { $return = fwrite($handle, $data); // Make sure that there's no trailing data by truncating the file to // the correct length: ftruncate($handle, strlen($data)); fflush($handle); flock($handle, LOCK_UN); } fclose($handle); if ($return !== false) { return true; } } // If we got this far, something went wrong with the file output... // It is tempting to throw an exception here, but this code is called // outside of the context of exception handling, so all we can do is // echo a message.

// Anecdotal testing Today and Yesterday seems to indicate destroy() // is called by the garbage collector and everything is good. // Something to keep in mind though. return 0; } /** * Write function that is called when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ public function write($sessId, $data): bool { if ($this->writesDisabled) { return true; } return $this->saveSession($sessId, $data); } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ abstract protected function saveSession($sessId, $data): bool; }

* * @return void */ public function writeClose() { // The assumption is that we're using PHP's ext/session. // session_write_close() will actually overwrite $_SESSION with an // empty array on completion -- which leads to a mismatch between what // is in the storage object and $_SESSION. To get around this, we // temporarily reset $_SESSION to an array, and then re-link it to // the storage object. // // Additionally, while you _can_ write to $_SESSION following a // session_write_close() operation, no changes made to it will be // flushed to the session handler. As such, we now mark the storage // object isImmutable. $storage = $this->getStorage(); if (! $storage->isImmutable()) { $_SESSION = $storage->toArray(true); session_write_close(); $storage->fromArray($_SESSION); $storage->markImmutable(); } } /** * Attempt to set the session name * * If the session has already been started, or if the name provided fails * validation, an exception will be raised. * * @param string $name * @return SessionManager * @throws Exception\InvalidArgumentException */ public function setName($name) { if ($this->sessionExists()) { throw new Exception\InvalidArgumentException( 'Cannot set session name after a session has already started'

Environment & details:

GET Data empty

POST Data empty

Files empty

Key	Value
VUFIND_SESSION	"74cbe74f4ffa95a2e096cd3c146b3f49"
language	"fr"
ui	"standard"

Session

Key	Value
__Laminas	array:2 [`"_REQUEST_ACCESS_TIME" => 1790867576.1492 "_VALID" => array:1 [ "Laminas\Session\Validator\Id" => "74cbe74f4ffa95a2e096cd3c146b3f49" ]`]
SessionState	Laminas\Stdlib\ArrayObject {#938}
FlashMessenger	Laminas\Stdlib\ArrayObject {#1433}
SessionHelper	Laminas\Stdlib\ArrayObject {#1759}

Server/Request Data

Key	Value
REDIRECT_VUFIND_LOCAL_DIR	"/usr/local/vufind/local"
REDIRECT_HTTPS	"on"
REDIRECT_SSL_TLS_SNI	"info.umar.mx"
REDIRECT_STATUS	"200"
VUFIND_LOCAL_DIR	"/usr/local/vufind/local"
HTTPS	"on"
SSL_TLS_SNI	"info.umar.mx"
HTTP_ACCEPT	"/"
HTTP_USER_AGENT	"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
HTTP_COOKIE	"VUFIND_SESSION=74cbe74f4ffa95a2e096cd3c146b3f49; language=fr; ui=standard"
HTTP_ACCEPT_ENCODING	"gzip, br, zstd, deflate"
HTTP_HOST	"info.umar.mx"
PATH	"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/snap/bin"
SERVER_SIGNATURE	"<address>Apache/2.4.66 (Ubuntu) Server at info.umar.mx Port 443</address>\n"
SERVER_SOFTWARE	"Apache/2.4.66 (Ubuntu)"
SERVER_NAME	"info.umar.mx"
SERVER_ADDR	"200.23.222.19"
SERVER_PORT	"443"
REMOTE_ADDR	"216.73.216.147"
DOCUMENT_ROOT	"/usr/local/vufind/public"
REQUEST_SCHEME	"https"
CONTEXT_PREFIX	""
CONTEXT_DOCUMENT_ROOT	"/usr/local/vufind/public"
SERVER_ADMIN	"admin@localhost"
SCRIPT_FILENAME	"/usr/local/vufind/public/index.php"
REMOTE_PORT	"53852"
REDIRECT_URL	""" /Record/\n arxiv_https___arxiv_org_abs_2512_24486/Similar """
GATEWAY_INTERFACE	"CGI/1.1"
SERVER_PROTOCOL	"HTTP/1.1"
REQUEST_METHOD	"GET"
QUERY_STRING	""
REQUEST_URI	"/Record/%0Aarxiv_https___arxiv_org_abs_2512_24486/Similar"
SCRIPT_NAME	"/index.php"
PHP_SELF	"/index.php"
REQUEST_TIME_FLOAT	1790867576.1452
REQUEST_TIME	1790867576

Environment Variables empty

Registered Handlers

0. Whoops\Handler\PrettyPageHandler