SRU-Pix2Pix: A Fusion-Driven Generator Network for Medical Image Translation with Few-Shot Learning

Fuente: arXiv
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Autores principales: Qiu, Xihe, Dai, Yang, Tan, Xiaoyu, Li, Sijia, Sun, Fenghao, Gan, Lu, Liu, Liang
Formato: Preprint
Publicado: 2026
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author Qiu, Xihe
Dai, Yang
Tan, Xiaoyu
Li, Sijia
Sun, Fenghao
Gan, Lu
Liu, Liang
author_facet Qiu, Xihe
Dai, Yang
Tan, Xiaoyu
Li, Sijia
Sun, Fenghao
Gan, Lu
Liu, Liang
contents Magnetic Resonance Imaging (MRI) provides detailed tissue information, but its clinical application is limited by long acquisition time, high cost, and restricted resolution. Image translation has recently gained attention as a strategy to address these limitations. Although Pix2Pix has been widely applied in medical image translation, its potential has not been fully explored. In this study, we propose an enhanced Pix2Pix framework that integrates Squeeze-and-Excitation Residual Networks (SEResNet) and U-Net++ to improve image generation quality and structural fidelity. SEResNet strengthens critical feature representation through channel attention, while U-Net++ enhances multi-scale feature fusion. A simplified PatchGAN discriminator further stabilizes training and refines local anatomical realism. Experimental results demonstrate that under few-shot conditions with fewer than 500 images, the proposed method achieves consistent structural fidelity and superior image quality across multiple intra-modality MRI translation tasks, showing strong generalization ability. These results suggest an effective extension of Pix2Pix for medical image translation.
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id arxiv_https___arxiv_org_abs_2601_04785
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle SRU-Pix2Pix: A Fusion-Driven Generator Network for Medical Image Translation with Few-Shot Learning
Qiu, Xihe
Dai, Yang
Tan, Xiaoyu
Li, Sijia
Sun, Fenghao
Gan, Lu
Liu, Liang
Computer Vision and Pattern Recognition
Artificial Intelligence
Magnetic Resonance Imaging (MRI) provides detailed tissue information, but its clinical application is limited by long acquisition time, high cost, and restricted resolution. Image translation has recently gained attention as a strategy to address these limitations. Although Pix2Pix has been widely applied in medical image translation, its potential has not been fully explored. In this study, we propose an enhanced Pix2Pix framework that integrates Squeeze-and-Excitation Residual Networks (SEResNet) and U-Net++ to improve image generation quality and structural fidelity. SEResNet strengthens critical feature representation through channel attention, while U-Net++ enhances multi-scale feature fusion. A simplified PatchGAN discriminator further stabilizes training and refines local anatomical realism. Experimental results demonstrate that under few-shot conditions with fewer than 500 images, the proposed method achieves consistent structural fidelity and superior image quality across multiple intra-modality MRI translation tasks, showing strong generalization ability. These results suggest an effective extension of Pix2Pix for medical image translation.
title SRU-Pix2Pix: A Fusion-Driven Generator Network for Medical Image Translation with Few-Shot Learning
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2601.04785