Co-doping of silicate bioceramics as a potential strategy to further enhance mono-doping consequences

Fuente: arXiv
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Autori principali: Mofakhami, Sohrab, Salahinejad, Erfan
Natura: Preprint
Pubblicazione: 2026
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author Mofakhami, Sohrab
Salahinejad, Erfan
author_facet Mofakhami, Sohrab
Salahinejad, Erfan
contents Silicate bioceramics have attracted significant attention in medical applications, particularly in hard tissue regeneration, because of their controllable chemical, physical, and biological functionalities, while ensuring biocompatibility. The coordination of silicate bioceramics with mono-dopants has been extensively studied to enhance their osteogenesis, angiogenesis, and antibacterial activity. However, the concept of employing dual or multiple co-doping to further enhance these biomaterials still demands more attention. This review paper originally focuses on the effect of chemical interactions among co-dopants and the principal constituents of the silicates, on the bio-behavior of these bioceramics. Additionally, future prospects of co-doped silicate bioceramics are outlined, including in vivo studies, clinical trials, and potential commercialization.
format Preprint
id arxiv_https___arxiv_org_abs_2601_06099
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Co-doping of silicate bioceramics as a potential strategy to further enhance mono-doping consequences
Mofakhami, Sohrab
Salahinejad, Erfan
Chemical Physics
Materials Science
Applied Physics
Biological Physics
Medical Physics
Silicate bioceramics have attracted significant attention in medical applications, particularly in hard tissue regeneration, because of their controllable chemical, physical, and biological functionalities, while ensuring biocompatibility. The coordination of silicate bioceramics with mono-dopants has been extensively studied to enhance their osteogenesis, angiogenesis, and antibacterial activity. However, the concept of employing dual or multiple co-doping to further enhance these biomaterials still demands more attention. This review paper originally focuses on the effect of chemical interactions among co-dopants and the principal constituents of the silicates, on the bio-behavior of these bioceramics. Additionally, future prospects of co-doped silicate bioceramics are outlined, including in vivo studies, clinical trials, and potential commercialization.
title Co-doping of silicate bioceramics as a potential strategy to further enhance mono-doping consequences
topic Chemical Physics
Materials Science
Applied Physics
Biological Physics
Medical Physics
url https://arxiv.org/abs/2601.06099