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Bibliographic Details
Main Authors: Speziale, Francesco, Lomoio, Ugo, Boccuto, Fabiola, Veltri, Pierangelo, Guzzi, Pietro Hiram
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2601.08260
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Table of Contents:
  • Cardiac amyloidosis (CA) is a rare and underdiagnosed infiltrative cardiomyopathy, and available datasets for machine-learning models are typically small, imbalanced and heterogeneous. This paper presents a Generative Adversarial Network (GAN) and a graphical command-line interface for generating realistic synthetic electrocardiogram (ECG) beats to support early diagnosis and patient stratification in CA. The tool is designed for usability, allowing clinical researchers to train class-specific generators once and then interactively produce large volumes of labelled synthetic beats that preserve the distribution of minority classes.