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| Natura: | Preprint |
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2026
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| Accesso online: | https://arxiv.org/abs/2601.14135 |
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| _version_ | 1866908776549842944 |
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| author | Mishra, Madhurendra Qi, Zhen Ganesan, Adarsh |
| author_facet | Mishra, Madhurendra Qi, Zhen Ganesan, Adarsh |
| contents | We investigate neuronal excitability in the Hodgkin-Huxley model under temporal interference (TI) stimulation in a previously unexplored sub-Hz resonant regime and uncover a striking nonlinear response that we term 'multi-tongue frequency fractals'. Unlike single-frequency driving, which yields a smooth resonant valley, dual-frequency excitation fragments this response into a hierarchy of sharply modulated tongues whose number and structure grow with observation time, revealing clear self-similar architecture. These features emerge from transitions between non-cascaded and cascaded high-harmonic and sub-harmonic generation as detuning varies, and are maximized near the intrinsic ionic timescale at omega ~ 0.2 rad/s. Parameter sweeps show that the fractal count is higher for higher potassium conductances, lower sodium conductances and lower leak conductances. These results demonstrate that TI stimulation can elicit rich, hierarchically organized frequency responses even in classical excitable membranes, revealing fractal organization in Hodgkin-Huxley dynamics. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2601_14135 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Multi-Tongue Frequency Fractal Dynamics in Hodgkin-Huxley Neurons Induced by Temporal Interference Stimulation Mishra, Madhurendra Qi, Zhen Ganesan, Adarsh Pattern Formation and Solitons We investigate neuronal excitability in the Hodgkin-Huxley model under temporal interference (TI) stimulation in a previously unexplored sub-Hz resonant regime and uncover a striking nonlinear response that we term 'multi-tongue frequency fractals'. Unlike single-frequency driving, which yields a smooth resonant valley, dual-frequency excitation fragments this response into a hierarchy of sharply modulated tongues whose number and structure grow with observation time, revealing clear self-similar architecture. These features emerge from transitions between non-cascaded and cascaded high-harmonic and sub-harmonic generation as detuning varies, and are maximized near the intrinsic ionic timescale at omega ~ 0.2 rad/s. Parameter sweeps show that the fractal count is higher for higher potassium conductances, lower sodium conductances and lower leak conductances. These results demonstrate that TI stimulation can elicit rich, hierarchically organized frequency responses even in classical excitable membranes, revealing fractal organization in Hodgkin-Huxley dynamics. |
| title | Multi-Tongue Frequency Fractal Dynamics in Hodgkin-Huxley Neurons Induced by Temporal Interference Stimulation |
| topic | Pattern Formation and Solitons |
| url | https://arxiv.org/abs/2601.14135 |