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| Autori principali: | , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2026
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| Soggetti: | |
| Accesso online: | https://arxiv.org/abs/2601.15502 |
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| _version_ | 1866917324010815488 |
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| author | Enríquez, T. Troncoso Staforelli-Vivanco, J. Bordeu, I. González-Ortiz, M. |
| author_facet | Enríquez, T. Troncoso Staforelli-Vivanco, J. Bordeu, I. González-Ortiz, M. |
| contents | This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of erythrocytes in different glucose environments. Our methodology integrates automated tracking via TrackMate\c{opyright} to analyze over 60 trajectory sets. The results reveal a significant decrease in mean velocity, from 11.8 μm/s in 5 mM glucose to 8.8 μm/s in 50 mM glucose (p = 0.019). These findings suggest that evanescent waves can serve as a non-invasive tool to probe the mechanical properties of cell membranes influenced by biochemical changes. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2601_15502 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Optical Manipulation of Erythrocytes via Evanescent Waves: Assessing Glucose-Induced Mobility Variations Enríquez, T. Troncoso Staforelli-Vivanco, J. Bordeu, I. González-Ortiz, M. Optics Biological Physics Cell Behavior Quantitative Methods This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of erythrocytes in different glucose environments. Our methodology integrates automated tracking via TrackMate\c{opyright} to analyze over 60 trajectory sets. The results reveal a significant decrease in mean velocity, from 11.8 μm/s in 5 mM glucose to 8.8 μm/s in 50 mM glucose (p = 0.019). These findings suggest that evanescent waves can serve as a non-invasive tool to probe the mechanical properties of cell membranes influenced by biochemical changes. |
| title | Optical Manipulation of Erythrocytes via Evanescent Waves: Assessing Glucose-Induced Mobility Variations |
| topic | Optics Biological Physics Cell Behavior Quantitative Methods |
| url | https://arxiv.org/abs/2601.15502 |