MRAG: Benchmarking Retrieval-Augmented Generation for Bio-medicine

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Hauptverfasser: Li, Liz, Zhu, Wei
Format: Preprint
Veröffentlicht: 2026
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author Li, Liz
Zhu, Wei
author_facet Li, Liz
Zhu, Wei
contents While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical Retrieval-Augmented Generation (MRAG) benchmark, covering various tasks in English and Chinese languages, and building a corpus with Wikipedia and Pubmed. Additionally, we develop the MRAG-Toolkit, facilitating systematic exploration of different RAG components. Our experiments reveal that: (a) RAG enhances LLM reliability across MRAG tasks. (b) the performance of RAG systems is influenced by retrieval approaches, model sizes, and prompting strategies. (c) While RAG improves usefulness and reasoning quality, LLM responses may become slightly less readable for long-form questions. We will release the MRAG-Bench's dataset and toolkit with CCBY-4.0 license upon acceptance, to facilitate applications from both academia and industry.
format Preprint
id arxiv_https___arxiv_org_abs_2601_16503
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle MRAG: Benchmarking Retrieval-Augmented Generation for Bio-medicine
Li, Liz
Zhu, Wei
Computation and Language
Artificial Intelligence
While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical Retrieval-Augmented Generation (MRAG) benchmark, covering various tasks in English and Chinese languages, and building a corpus with Wikipedia and Pubmed. Additionally, we develop the MRAG-Toolkit, facilitating systematic exploration of different RAG components. Our experiments reveal that: (a) RAG enhances LLM reliability across MRAG tasks. (b) the performance of RAG systems is influenced by retrieval approaches, model sizes, and prompting strategies. (c) While RAG improves usefulness and reasoning quality, LLM responses may become slightly less readable for long-form questions. We will release the MRAG-Bench's dataset and toolkit with CCBY-4.0 license upon acceptance, to facilitate applications from both academia and industry.
title MRAG: Benchmarking Retrieval-Augmented Generation for Bio-medicine
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2601.16503