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Autores principales: Li, Xiaoyang, Zhou, Runni, Yan, Xinghao, Yan, Liehao, Li, Zhaochen, Zhu, Chenjie, Fu, Rongrong, Chai, Yuan
Formato: Preprint
Publicado: 2026
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Acceso en línea:https://arxiv.org/abs/2601.17336
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author Li, Xiaoyang
Zhou, Runni
Yan, Xinghao
Yan, Liehao
Li, Zhaochen
Zhu, Chenjie
Fu, Rongrong
Chai, Yuan
author_facet Li, Xiaoyang
Zhou, Runni
Yan, Xinghao
Yan, Liehao
Li, Zhaochen
Zhu, Chenjie
Fu, Rongrong
Chai, Yuan
contents Automated Kellgren--Lawrence (KL) grading from knee radiographs is challenging due to subtle structural changes, long-range anatomical dependencies, and ambiguity near grade boundaries. We propose AGE-Net, a ConvNeXt-based framework that integrates Spectral--Spatial Fusion (SSF), Anatomical Graph Reasoning (AGR), and Differential Refinement (DFR). To capture predictive uncertainty and preserve label ordinality, AGE-Net employs a Normal-Inverse-Gamma (NIG) evidential regression head and a pairwise ordinal ranking constraint. On a knee KL dataset, AGE-Net achieves a quadratic weighted kappa (QWK) of 0.9017 +/- 0.0045 and a mean squared error (MSE) of 0.2349 +/- 0.0028 over three random seeds, outperforming strong CNN baselines and showing consistent gains in ablation studies. We further outline evaluations of uncertainty quality, robustness, and explainability, with additional experimental figures to be included in the full manuscript.
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spellingShingle AGE-Net: Spectral--Spatial Fusion and Anatomical Graph Reasoning with Evidential Ordinal Regression for Knee Osteoarthritis Grading
Li, Xiaoyang
Zhou, Runni
Yan, Xinghao
Yan, Liehao
Li, Zhaochen
Zhu, Chenjie
Fu, Rongrong
Chai, Yuan
Computer Vision and Pattern Recognition
Automated Kellgren--Lawrence (KL) grading from knee radiographs is challenging due to subtle structural changes, long-range anatomical dependencies, and ambiguity near grade boundaries. We propose AGE-Net, a ConvNeXt-based framework that integrates Spectral--Spatial Fusion (SSF), Anatomical Graph Reasoning (AGR), and Differential Refinement (DFR). To capture predictive uncertainty and preserve label ordinality, AGE-Net employs a Normal-Inverse-Gamma (NIG) evidential regression head and a pairwise ordinal ranking constraint. On a knee KL dataset, AGE-Net achieves a quadratic weighted kappa (QWK) of 0.9017 +/- 0.0045 and a mean squared error (MSE) of 0.2349 +/- 0.0028 over three random seeds, outperforming strong CNN baselines and showing consistent gains in ablation studies. We further outline evaluations of uncertainty quality, robustness, and explainability, with additional experimental figures to be included in the full manuscript.
title AGE-Net: Spectral--Spatial Fusion and Anatomical Graph Reasoning with Evidential Ordinal Regression for Knee Osteoarthritis Grading
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2601.17336