GPCR-Filter: a deep learning framework for efficient and precise GPCR modulator discovery
Fuente:
arXiv
Saved in:
| Main Authors: | Ning, Jingjie, Shen, Xiangzhen, Hou, Li, Shen, Shiyi, Yang, Jiahao, Li, Junrui, Shan, Hong, Wu, Sanan, Gao, Sihan, Xu, H. Eric, He, Xinheng |
|---|---|
| Format: | Preprint |
| Published: |
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
All-Atom GPCR-Ligand Simulation via Residual Isometric Latent Flow
by: Zhang, Jiying, et al.
Published: (2026)
by: Zhang, Jiying, et al.
Published: (2026)
Explainable deep learning framework for cancer therapeutic target prioritization leveraging PPI centrality and node embeddings
by: Alkhadrawi, Adham M., et al.
Published: (2025)
by: Alkhadrawi, Adham M., et al.
Published: (2025)
Physics-informed deep learning for infectious disease forecasting
by: Qian, Ying, et al.
Published: (2025)
by: Qian, Ying, et al.
Published: (2025)
Physics‐informed multimodal learning for snapshot dental spectral reflectance prediction
by: Yujun Feng, et al.
Published: (2026)
by: Yujun Feng, et al.
Published: (2026)
GPCR dimerization: Drug discovery aspects and targets in renin‐angiotensin systems
by: Tahmid Faisal, et al.
Published: (2025)
by: Tahmid Faisal, et al.
Published: (2025)
IgCraft: A versatile sequence generation framework for antibody discovery and engineering
by: Greenig, Matthew, et al.
Published: (2025)
by: Greenig, Matthew, et al.
Published: (2025)
Geometric deep learning assists protein engineering. Opportunities and Challenges
by: García-Vinuesa, Julián, et al.
Published: (2025)
by: García-Vinuesa, Julián, et al.
Published: (2025)
Accurate RNA 3D structure prediction using a language model-based deep learning approach
by: Shen, Tao, et al.
Published: (2022)
by: Shen, Tao, et al.
Published: (2022)
Analyzing animal movement using deep learning
by: Fronville, Thibault, et al.
Published: (2026)
by: Fronville, Thibault, et al.
Published: (2026)
Resolving the bias-precision paradox with stochastic causal representation learning for personalized medicine
by: Zhang, Peisong, et al.
Published: (2026)
by: Zhang, Peisong, et al.
Published: (2026)
Data-driven discovery of dynamical models in biology
by: Prokop, Bartosz, et al.
Published: (2025)
by: Prokop, Bartosz, et al.
Published: (2025)
Drug discovery guided by maximum drug likeness
by: Zhu, Hao-Yu, et al.
Published: (2025)
by: Zhu, Hao-Yu, et al.
Published: (2025)
Nonparametric causal discovery with applications to cancer bioinformatics
by: Gomez, Jean Pierre
Published: (2023)
by: Gomez, Jean Pierre
Published: (2023)
Recent advances in deep learning and language models for studying the microbiome
by: Yan, Binghao, et al.
Published: (2024)
by: Yan, Binghao, et al.
Published: (2024)
GPCR microswitch analysis scripts and data
by: Ji, Jingjing, et al.
Published: (2026)
by: Ji, Jingjing, et al.
Published: (2026)
Mechanisms governing GPCR anterograde transport
by: Kevin Assoumou, et al.
Published: (2025)
by: Kevin Assoumou, et al.
Published: (2025)
Artificial intelligence in drug discovery: A comprehensive review with a case study on hyperuricemia, gout arthritis, and hyperuricemic nephropathy
by: Su, Junwei, et al.
Published: (2025)
by: Su, Junwei, et al.
Published: (2025)
Self-evolving AI agents for protein discovery and directed evolution
by: Tan, Yang, et al.
Published: (2026)
by: Tan, Yang, et al.
Published: (2026)
Improving AlphaFlow for Efficient Protein Ensembles Generation
by: Li, Shaoning, et al.
Published: (2024)
by: Li, Shaoning, et al.
Published: (2024)
Biodiversity2Drugs—Renaissance of exploring nature‐derived peptides for GPCR ligand discovery
by: Christian W. Gruber, et al.
Published: (2025)
by: Christian W. Gruber, et al.
Published: (2025)
Opportunities in deep learning methods development for computational biology
by: Lee, Alex Jihun, et al.
Published: (2024)
by: Lee, Alex Jihun, et al.
Published: (2024)
An information-based model selection criterion for data-driven model discovery
by: Chung, Michael C, et al.
Published: (2026)
by: Chung, Michael C, et al.
Published: (2026)
Bayesian ensemble learning for predicting health outcomes of multipollutant mixtures
by: Ning, Yu-Chien, et al.
Published: (2025)
by: Ning, Yu-Chien, et al.
Published: (2025)
Quantum machine learning framework for longitudinal biomedical studies
by: Demidik, Maria, et al.
Published: (2025)
by: Demidik, Maria, et al.
Published: (2025)
GenoHoption: Bridging Gene Network Graphs and Single-Cell Foundation Models
by: Cheng, Jiabei, et al.
Published: (2024)
by: Cheng, Jiabei, et al.
Published: (2024)
Integrating protein sequence embeddings with structure via graph-based deep learning for single-residue property prediction
by: Michalewicz, Kevin, et al.
Published: (2025)
by: Michalewicz, Kevin, et al.
Published: (2025)
A comprehensive review of molecular optimization in artificial intelligence‐based drug discovery
by: Yuhang Xia, et al.
Published: (2024)
by: Yuhang Xia, et al.
Published: (2024)
Experts' cognition-driven safe noisy labels learning for precise segmentation of residual tumor in breast cancer
by: Yang, Yongquan, et al.
Published: (2023)
by: Yang, Yongquan, et al.
Published: (2023)
Epidemic-guided deep learning for spatiotemporal forecasting of Tuberculosis outbreak
by: Barman, Madhab, et al.
Published: (2025)
by: Barman, Madhab, et al.
Published: (2025)
deepNoC: A deep learning system to assign the number of contributors to a short tandem repeat DNA profile
by: Taylor, Duncan, et al.
Published: (2024)
by: Taylor, Duncan, et al.
Published: (2024)
SPECIFIC: A systematic framework for engineering cell state‐responsive synthetic promoters reveals key regulators of T cell exhaustion
by: Zhaoyu Zhang, et al.
Published: (2025)
by: Zhaoyu Zhang, et al.
Published: (2025)
Benchmarking open-source tools for in silico antiviral drug discovery
by: Elton, Daniel C., et al.
Published: (2026)
by: Elton, Daniel C., et al.
Published: (2026)
Decoding the dark proteome: Deep learning-enabled discovery of druggable enzymes in Wuchereria bancrofti
by: Shivakumar, Shawnak, et al.
Published: (2025)
by: Shivakumar, Shawnak, et al.
Published: (2025)
Why we need all the organisms: an exploration of the Monarch knowledge graph to aid mechanism discovery
by: Cortes, Katherina, et al.
Published: (2025)
by: Cortes, Katherina, et al.
Published: (2025)
Structuring the GPCR Story Through the Lens of NMR
by: Arpita Prasad, et al.
Published: (2025)
by: Arpita Prasad, et al.
Published: (2025)
The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma
by: Ana B. Caniceiro, et al.
Published: (2026)
by: Ana B. Caniceiro, et al.
Published: (2026)
A penalized integrative deep neural network for variable selection among multiple omics datasets
by: Yang Li, et al.
Published: (2024)
by: Yang Li, et al.
Published: (2024)
Simultaneously Infer Cell Pseudotime,Velocity Field and Gene Interaction from Multi-Branch scRNA-seq Data with scPN
by: Zhou, Zhen, et al.
Published: (2024)
by: Zhou, Zhen, et al.
Published: (2024)
Data-centric challenges with the application and adoption of artificial intelligence for drug discovery
by: Ghislat, Ghita, et al.
Published: (2024)
by: Ghislat, Ghita, et al.
Published: (2024)
Disentangling coincident cell events using deep transfer learning and compressive sensing
by: Leuthner, Moritz, et al.
Published: (2025)
by: Leuthner, Moritz, et al.
Published: (2025)
Similar Items
-
All-Atom GPCR-Ligand Simulation via Residual Isometric Latent Flow
by: Zhang, Jiying, et al.
Published: (2026) -
Explainable deep learning framework for cancer therapeutic target prioritization leveraging PPI centrality and node embeddings
by: Alkhadrawi, Adham M., et al.
Published: (2025) -
Physics-informed deep learning for infectious disease forecasting
by: Qian, Ying, et al.
Published: (2025) -
Physics‐informed multimodal learning for snapshot dental spectral reflectance prediction
by: Yujun Feng, et al.
Published: (2026) -
GPCR dimerization: Drug discovery aspects and targets in renin‐angiotensin systems
by: Tahmid Faisal, et al.
Published: (2025)