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Main Authors: Rasel, M. A., Kareem, Sameem Abdul, Obaidellah, Unaizah
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2601.20869
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author Rasel, M. A.
Kareem, Sameem Abdul
Obaidellah, Unaizah
author_facet Rasel, M. A.
Kareem, Sameem Abdul
Obaidellah, Unaizah
contents The color of skin lesions is an important diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue gray. This study introduces a novel feature: the number of colors present in a lesion, which can indicate the severity of disease and help distinguish melanomas from benign lesions. We propose a color histogram analysis method to examine lesion pixel values from three publicly available datasets: PH2, ISIC2016, and Med Node. The PH2 dataset contains ground truth annotations of lesion colors, while ISIC2016 and Med Node do not; our algorithm estimates the ground truth using color histogram analysis based on PH2. We then design and train a 19 layer Convolutional Neural Network (CNN) with residual skip connections to classify lesions into three categories based on the number of colors present. DeepDream visualization is used to interpret features learned by the network, and multiple CNN configurations are tested. The best model achieves a weighted F1 score of 75 percent. LIME is applied to identify important regions influencing model decisions. The results show that the number of colors in a lesion is a significant feature for describing skin conditions, and the proposed CNN with three skip connections demonstrates strong potential for clinical diagnostic support.
format Preprint
id arxiv_https___arxiv_org_abs_2601_20869
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publishDate 2026
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spellingShingle Integrating Color Histogram Analysis and Convolutional Neural Network for Skin Lesion Classification
Rasel, M. A.
Kareem, Sameem Abdul
Obaidellah, Unaizah
Quantitative Methods
Artificial Intelligence
Image and Video Processing
The color of skin lesions is an important diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue gray. This study introduces a novel feature: the number of colors present in a lesion, which can indicate the severity of disease and help distinguish melanomas from benign lesions. We propose a color histogram analysis method to examine lesion pixel values from three publicly available datasets: PH2, ISIC2016, and Med Node. The PH2 dataset contains ground truth annotations of lesion colors, while ISIC2016 and Med Node do not; our algorithm estimates the ground truth using color histogram analysis based on PH2. We then design and train a 19 layer Convolutional Neural Network (CNN) with residual skip connections to classify lesions into three categories based on the number of colors present. DeepDream visualization is used to interpret features learned by the network, and multiple CNN configurations are tested. The best model achieves a weighted F1 score of 75 percent. LIME is applied to identify important regions influencing model decisions. The results show that the number of colors in a lesion is a significant feature for describing skin conditions, and the proposed CNN with three skip connections demonstrates strong potential for clinical diagnostic support.
title Integrating Color Histogram Analysis and Convolutional Neural Network for Skin Lesion Classification
topic Quantitative Methods
Artificial Intelligence
Image and Video Processing
url https://arxiv.org/abs/2601.20869