Sustainable Materials Discovery in the Era of Artificial Intelligence

Fuente: arXiv
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Main Authors: Mannan, Sajid, Myers, Rupert J., Batra, Rohit, Mercado, Rocio, Wondraczek, Lothar, Krishnan, N. M. Anoop
Format: Preprint
Published: 2026
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author Mannan, Sajid
Myers, Rupert J.
Batra, Rohit
Mercado, Rocio
Wondraczek, Lothar
Krishnan, N. M. Anoop
author_facet Mannan, Sajid
Myers, Rupert J.
Batra, Rohit
Mercado, Rocio
Wondraczek, Lothar
Krishnan, N. M. Anoop
contents Artificial intelligence (AI) has transformed materials discovery, enabling rapid exploration of chemical space through generative models and surrogate screening. Yet current AI workflows optimize performance first, deferring sustainability to post synthesis assessment. This creates inefficiency by the time environmental burdens are quantified, resources have been invested in potentially unsustainable solutions. The disconnect between atomic scale design and lifecycle assessment (LCA) reflects fundamental challenges, data scarcity across heterogeneous sources, scale gaps from atoms to industrial systems, uncertainty in synthesis pathways, and the absence of frameworks that co-optimize performance with environmental impact. We propose to integrate upstream machine learning (ML) assisted materials discovery with downstream lifecycle assessment into a uniform ML-LCA environment. The framework ML-LCA integrates five components, information extraction for building materials-environment knowledge bases, harmonized databases linking properties to sustainability metrics, multi-scale models bridging atomic properties to lifecycle impacts, ensemble prediction of manufacturing pathways with uncertainty quantification, and uncertainty-aware optimization enabling simultaneous performance-sustainability navigation. Case studies spanning glass, cement, semiconductor photoresists, and polymers demonstrate both necessity and feasibility while identifying material-specific integration challenges. Realizing ML-LCA demands coordinated advances in data infrastructure, ex-ante assessment methodologies, multi-objective optimization, and regulatory alignment enabling the discovery of materials that are sustainable by design rather than by chance.
format Preprint
id arxiv_https___arxiv_org_abs_2601_21527
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Sustainable Materials Discovery in the Era of Artificial Intelligence
Mannan, Sajid
Myers, Rupert J.
Batra, Rohit
Mercado, Rocio
Wondraczek, Lothar
Krishnan, N. M. Anoop
Materials Science
Artificial Intelligence
Artificial intelligence (AI) has transformed materials discovery, enabling rapid exploration of chemical space through generative models and surrogate screening. Yet current AI workflows optimize performance first, deferring sustainability to post synthesis assessment. This creates inefficiency by the time environmental burdens are quantified, resources have been invested in potentially unsustainable solutions. The disconnect between atomic scale design and lifecycle assessment (LCA) reflects fundamental challenges, data scarcity across heterogeneous sources, scale gaps from atoms to industrial systems, uncertainty in synthesis pathways, and the absence of frameworks that co-optimize performance with environmental impact. We propose to integrate upstream machine learning (ML) assisted materials discovery with downstream lifecycle assessment into a uniform ML-LCA environment. The framework ML-LCA integrates five components, information extraction for building materials-environment knowledge bases, harmonized databases linking properties to sustainability metrics, multi-scale models bridging atomic properties to lifecycle impacts, ensemble prediction of manufacturing pathways with uncertainty quantification, and uncertainty-aware optimization enabling simultaneous performance-sustainability navigation. Case studies spanning glass, cement, semiconductor photoresists, and polymers demonstrate both necessity and feasibility while identifying material-specific integration challenges. Realizing ML-LCA demands coordinated advances in data infrastructure, ex-ante assessment methodologies, multi-objective optimization, and regulatory alignment enabling the discovery of materials that are sustainable by design rather than by chance.
title Sustainable Materials Discovery in the Era of Artificial Intelligence
topic Materials Science
Artificial Intelligence
url https://arxiv.org/abs/2601.21527