OneFlowSBI: One Model, Many Queries for Simulation-Based Inference

Fuente: arXiv
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Main Authors: Nautiyal, Mayank, Ju, Li, Ernfors, Melker, Hagland, Klara, Holma, Ville, Söderholm, Maximilian Werkö, Hellander, Andreas, Singh, Prashant
Format: Preprint
Published: 2026
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author Nautiyal, Mayank
Ju, Li
Ernfors, Melker
Hagland, Klara
Holma, Ville
Söderholm, Maximilian Werkö
Hellander, Andreas
Singh, Prashant
author_facet Nautiyal, Mayank
Ju, Li
Ernfors, Melker
Hagland, Klara
Holma, Ville
Söderholm, Maximilian Werkö
Hellander, Andreas
Singh, Prashant
contents We introduce \textit{OneFlowSBI}, a unified framework for simulation-based inference that learns a single flow-matching generative model over the joint distribution of parameters and observations. Leveraging a query-aware masking distribution during training, the same model supports multiple inference tasks, including posterior sampling, likelihood estimation, and arbitrary conditional distributions, without task-specific retraining. We evaluate \textit{OneFlowSBI} on ten benchmark inference problems and two high-dimensional real-world inverse problems across multiple simulation budgets. \textit{OneFlowSBI} is shown to deliver competitive performance against state-of-the-art generalized inference solvers and specialized posterior estimators, while enabling efficient sampling with few ODE integration steps and remaining robust under noisy and partially observed data.
format Preprint
id arxiv_https___arxiv_org_abs_2601_22951
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle OneFlowSBI: One Model, Many Queries for Simulation-Based Inference
Nautiyal, Mayank
Ju, Li
Ernfors, Melker
Hagland, Klara
Holma, Ville
Söderholm, Maximilian Werkö
Hellander, Andreas
Singh, Prashant
Machine Learning
We introduce \textit{OneFlowSBI}, a unified framework for simulation-based inference that learns a single flow-matching generative model over the joint distribution of parameters and observations. Leveraging a query-aware masking distribution during training, the same model supports multiple inference tasks, including posterior sampling, likelihood estimation, and arbitrary conditional distributions, without task-specific retraining. We evaluate \textit{OneFlowSBI} on ten benchmark inference problems and two high-dimensional real-world inverse problems across multiple simulation budgets. \textit{OneFlowSBI} is shown to deliver competitive performance against state-of-the-art generalized inference solvers and specialized posterior estimators, while enabling efficient sampling with few ODE integration steps and remaining robust under noisy and partially observed data.
title OneFlowSBI: One Model, Many Queries for Simulation-Based Inference
topic Machine Learning
url https://arxiv.org/abs/2601.22951