MedMCP-Calc: Benchmarking LLMs for Realistic Medical Calculator Scenarios via MCP Integration

Fuente: arXiv
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Main Authors: Zhu, Yakun, Huang, Yutong, Qin, Shengqian, Huang, Zhongzhen, Zhang, Shaoting, Zhang, Xiaofan
Format: Preprint
Published: 2026
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author Zhu, Yakun
Huang, Yutong
Qin, Shengqian
Huang, Zhongzhen
Zhang, Shaoting
Zhang, Xiaofan
author_facet Zhu, Yakun
Huang, Yutong
Qin, Shengqian
Huang, Zhongzhen
Zhang, Shaoting
Zhang, Xiaofan
contents Medical calculators are fundamental to quantitative, evidence-based clinical practice. However, their real-world use is an adaptive, multi-stage process, requiring proactive EHR data acquisition, scenario-dependent calculator selection, and multi-step computation, whereas current benchmarks focus only on static single-step calculations with explicit instructions. To address these limitations, we introduce MedMCP-Calc, the first benchmark for evaluating LLMs in realistic medical calculator scenarios through Model Context Protocol (MCP) integration. MedMCP-Calc comprises 118 scenario tasks across 4 clinical domains, featuring fuzzy task descriptions mimicking natural queries, structured EHR database interaction, external reference retrieval, and process-level evaluation. Our evaluation of 23 leading models reveals critical limitations: even top performers like Claude Opus 4.5 exhibit substantial gaps, including difficulty selecting appropriate calculators for end-to-end workflows given fuzzy queries, poor performance in iterative SQL-based database interactions, and marked reluctance to leverage external tools for numerical computation. Performance also varies considerably across clinical domains. Building on these findings, we develop CalcMate, a fine-tuned model incorporating scenario planning and tool augmentation, achieving state-of-the-art performance among open-source models. Benchmark and Codes are available in https://github.com/SPIRAL-MED/MedMCP-Calc.
format Preprint
id arxiv_https___arxiv_org_abs_2601_23049
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle MedMCP-Calc: Benchmarking LLMs for Realistic Medical Calculator Scenarios via MCP Integration
Zhu, Yakun
Huang, Yutong
Qin, Shengqian
Huang, Zhongzhen
Zhang, Shaoting
Zhang, Xiaofan
Artificial Intelligence
Medical calculators are fundamental to quantitative, evidence-based clinical practice. However, their real-world use is an adaptive, multi-stage process, requiring proactive EHR data acquisition, scenario-dependent calculator selection, and multi-step computation, whereas current benchmarks focus only on static single-step calculations with explicit instructions. To address these limitations, we introduce MedMCP-Calc, the first benchmark for evaluating LLMs in realistic medical calculator scenarios through Model Context Protocol (MCP) integration. MedMCP-Calc comprises 118 scenario tasks across 4 clinical domains, featuring fuzzy task descriptions mimicking natural queries, structured EHR database interaction, external reference retrieval, and process-level evaluation. Our evaluation of 23 leading models reveals critical limitations: even top performers like Claude Opus 4.5 exhibit substantial gaps, including difficulty selecting appropriate calculators for end-to-end workflows given fuzzy queries, poor performance in iterative SQL-based database interactions, and marked reluctance to leverage external tools for numerical computation. Performance also varies considerably across clinical domains. Building on these findings, we develop CalcMate, a fine-tuned model incorporating scenario planning and tool augmentation, achieving state-of-the-art performance among open-source models. Benchmark and Codes are available in https://github.com/SPIRAL-MED/MedMCP-Calc.
title MedMCP-Calc: Benchmarking LLMs for Realistic Medical Calculator Scenarios via MCP Integration
topic Artificial Intelligence
url https://arxiv.org/abs/2601.23049