Chained Prompting for Better Systematic Review Search Strategies

Fuente: arXiv
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Autores principales: Nasser, Fatima, Trad, Fouad, Mohanna, Ammar, Fuleihan, Ghada El-Hajj, Chehab, Ali
Formato: Preprint
Publicado: 2025
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author Nasser, Fatima
Trad, Fouad
Mohanna, Ammar
Fuleihan, Ghada El-Hajj
Chehab, Ali
author_facet Nasser, Fatima
Trad, Fouad
Mohanna, Ammar
Fuleihan, Ghada El-Hajj
Chehab, Ali
contents Systematic reviews require the use of rigorously designed search strategies to ensure both comprehensive retrieval and minimization of bias. Conventional manual approaches, although methodologically systematic, are resource-intensive and susceptible to subjectivity, whereas heuristic and automated techniques frequently under-perform in recall unless supplemented by extensive expert input. We introduce a Large Language Model (LLM)-based chained prompt engineering framework for the automated development of search strategies in systematic reviews. The framework replicates the procedural structure of manual search design while leveraging LLMs to decompose review objectives, extract and formalize PICO elements, generate conceptual representations, expand terminologies, and synthesize Boolean queries. In addition to query construction, the framework exhibits superior performance in generating well-structured PICO elements relative to existing methods, thereby strengthening the foundation for high-recall search strategies. Evaluation on a subset of the LEADSInstruct dataset demonstrates that the framework attains a 0.9 average recall. These results significantly exceed the performance of existing approaches. Error analysis further highlights the critical role of precise objective specification and terminological alignment in optimizing retrieval effectiveness. These findings confirm the capacity of LLM-based pipelines to yield transparent, reproducible, and high-performing search strategies, and highlight their potential as scalable instruments for supporting evidence synthesis and evidence-based practice.
format Preprint
id arxiv_https___arxiv_org_abs_2602_00011
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Chained Prompting for Better Systematic Review Search Strategies
Nasser, Fatima
Trad, Fouad
Mohanna, Ammar
Fuleihan, Ghada El-Hajj
Chehab, Ali
Information Retrieval
Artificial Intelligence
Computation and Language
Systematic reviews require the use of rigorously designed search strategies to ensure both comprehensive retrieval and minimization of bias. Conventional manual approaches, although methodologically systematic, are resource-intensive and susceptible to subjectivity, whereas heuristic and automated techniques frequently under-perform in recall unless supplemented by extensive expert input. We introduce a Large Language Model (LLM)-based chained prompt engineering framework for the automated development of search strategies in systematic reviews. The framework replicates the procedural structure of manual search design while leveraging LLMs to decompose review objectives, extract and formalize PICO elements, generate conceptual representations, expand terminologies, and synthesize Boolean queries. In addition to query construction, the framework exhibits superior performance in generating well-structured PICO elements relative to existing methods, thereby strengthening the foundation for high-recall search strategies. Evaluation on a subset of the LEADSInstruct dataset demonstrates that the framework attains a 0.9 average recall. These results significantly exceed the performance of existing approaches. Error analysis further highlights the critical role of precise objective specification and terminological alignment in optimizing retrieval effectiveness. These findings confirm the capacity of LLM-based pipelines to yield transparent, reproducible, and high-performing search strategies, and highlight their potential as scalable instruments for supporting evidence synthesis and evidence-based practice.
title Chained Prompting for Better Systematic Review Search Strategies
topic Information Retrieval
Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2602.00011