Physiology as Language: Translating Respiration to Sleep EEG

Fuente: arXiv
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Autori principali: Zha, Kaiwen, Li, Chao, He, Hao, Cao, Peng, Li, Tianhong, Mirzazadeh, Ali, Zhang, Ellen, Lee, Jong Woo, Kim, Yoon, Katabi, Dina
Natura: Preprint
Pubblicazione: 2026
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author Zha, Kaiwen
Li, Chao
He, Hao
Cao, Peng
Li, Tianhong
Mirzazadeh, Ali
Zhang, Ellen
Lee, Jong Woo
Kim, Yoon
Katabi, Dina
author_facet Zha, Kaiwen
Li, Chao
He, Hao
Cao, Peng
Li, Tianhong
Mirzazadeh, Ali
Zhang, Ellen
Lee, Jong Woo
Kim, Yoon
Katabi, Dina
contents This paper introduces a novel cross-physiology translation task: synthesizing sleep electroencephalography (EEG) from respiration signals. To address the significant complexity gap between the two modalities, we propose a waveform-conditional generative framework that preserves fine-grained respiratory dynamics while constraining the EEG target space through discrete tokenization. Trained on over 28,000 individuals, our model achieves a 7% Mean Absolute Error in EEG spectrogram reconstruction. Beyond reconstruction, the synthesized EEG supports downstream tasks with performance comparable to ground truth EEG on age estimation (MAE 5.0 vs. 5.1 years), sex detection (AUROC 0.81 vs. 0.82), and sleep staging (Accuracy 0.84 vs. 0.88), significantly outperforming baselines trained directly on breathing. Finally, we demonstrate that the framework generalizes to contactless sensing by synthesizing EEG from wireless radio-frequency reflections, highlighting the feasibility of remote, non-contact neurological assessment during sleep.
format Preprint
id arxiv_https___arxiv_org_abs_2602_00526
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Physiology as Language: Translating Respiration to Sleep EEG
Zha, Kaiwen
Li, Chao
He, Hao
Cao, Peng
Li, Tianhong
Mirzazadeh, Ali
Zhang, Ellen
Lee, Jong Woo
Kim, Yoon
Katabi, Dina
Machine Learning
Artificial Intelligence
This paper introduces a novel cross-physiology translation task: synthesizing sleep electroencephalography (EEG) from respiration signals. To address the significant complexity gap between the two modalities, we propose a waveform-conditional generative framework that preserves fine-grained respiratory dynamics while constraining the EEG target space through discrete tokenization. Trained on over 28,000 individuals, our model achieves a 7% Mean Absolute Error in EEG spectrogram reconstruction. Beyond reconstruction, the synthesized EEG supports downstream tasks with performance comparable to ground truth EEG on age estimation (MAE 5.0 vs. 5.1 years), sex detection (AUROC 0.81 vs. 0.82), and sleep staging (Accuracy 0.84 vs. 0.88), significantly outperforming baselines trained directly on breathing. Finally, we demonstrate that the framework generalizes to contactless sensing by synthesizing EEG from wireless radio-frequency reflections, highlighting the feasibility of remote, non-contact neurological assessment during sleep.
title Physiology as Language: Translating Respiration to Sleep EEG
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2602.00526