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Autores principales: Peng, Jingjing, Fiore, Giorgio, Liu, Yang, Ellum, Ksenia, Daspupta, Debayan, Ashkan, Keyoumars, McEvoy, Andrew, Miserocchi, Anna, Ourselin, Sebastien, Duncan, John, Granados, Alejandro
Formato: Preprint
Publicado: 2026
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Acceso en línea:https://arxiv.org/abs/2602.03785
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author Peng, Jingjing
Fiore, Giorgio
Liu, Yang
Ellum, Ksenia
Daspupta, Debayan
Ashkan, Keyoumars
McEvoy, Andrew
Miserocchi, Anna
Ourselin, Sebastien
Duncan, John
Granados, Alejandro
author_facet Peng, Jingjing
Fiore, Giorgio
Liu, Yang
Ellum, Ksenia
Daspupta, Debayan
Ashkan, Keyoumars
McEvoy, Andrew
Miserocchi, Anna
Ourselin, Sebastien
Duncan, John
Granados, Alejandro
contents Introduction: In neurosurgery, image-guided Neurosurgery Systems (IGNS) highly rely on preoperative brain magnetic resonance images (MRI) to assist surgeons in locating surgical targets and determining surgical paths. However, brain shift invalidates the preoperative MRI after dural opening. Updated intraoperative brain MRI with brain shift compensation is crucial for enhancing the precision of neuronavigation systems and ensuring the optimal outcome of surgical interventions. Methodology: We propose NeuralShift, a U-Net-based model that predicts brain shift entirely from pre-operative MRI for patients undergoing temporal lobe resection. We evaluated our results using Target Registration Errors (TREs) computed on anatomical landmarks located on the resection side and along the midline, and DICE scores comparing predicted intraoperative masks with masks derived from intraoperative MRI. Results: Our experimental results show that our model can predict the global deformation of the brain (DICE of 0.97) with accurate local displacements (achieve landmark TRE as low as 1.12 mm), compensating for large brain shifts during temporal lobe removal neurosurgery. Conclusion: Our proposed model is capable of predicting the global deformation of the brain during temporal lobe resection using only preoperative images, providing potential opportunities to the surgical team to increase safety and efficiency of neurosurgery and better outcomes to patients. Our contributions will be publicly available after acceptance in https://github.com/SurgicalDataScienceKCL/NeuralShift.
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spellingShingle From Pre- to Intra-operative MRI: Predicting Brain Shift in Temporal Lobe Resection for Epilepsy Surgery
Peng, Jingjing
Fiore, Giorgio
Liu, Yang
Ellum, Ksenia
Daspupta, Debayan
Ashkan, Keyoumars
McEvoy, Andrew
Miserocchi, Anna
Ourselin, Sebastien
Duncan, John
Granados, Alejandro
Computer Vision and Pattern Recognition
Introduction: In neurosurgery, image-guided Neurosurgery Systems (IGNS) highly rely on preoperative brain magnetic resonance images (MRI) to assist surgeons in locating surgical targets and determining surgical paths. However, brain shift invalidates the preoperative MRI after dural opening. Updated intraoperative brain MRI with brain shift compensation is crucial for enhancing the precision of neuronavigation systems and ensuring the optimal outcome of surgical interventions. Methodology: We propose NeuralShift, a U-Net-based model that predicts brain shift entirely from pre-operative MRI for patients undergoing temporal lobe resection. We evaluated our results using Target Registration Errors (TREs) computed on anatomical landmarks located on the resection side and along the midline, and DICE scores comparing predicted intraoperative masks with masks derived from intraoperative MRI. Results: Our experimental results show that our model can predict the global deformation of the brain (DICE of 0.97) with accurate local displacements (achieve landmark TRE as low as 1.12 mm), compensating for large brain shifts during temporal lobe removal neurosurgery. Conclusion: Our proposed model is capable of predicting the global deformation of the brain during temporal lobe resection using only preoperative images, providing potential opportunities to the surgical team to increase safety and efficiency of neurosurgery and better outcomes to patients. Our contributions will be publicly available after acceptance in https://github.com/SurgicalDataScienceKCL/NeuralShift.
title From Pre- to Intra-operative MRI: Predicting Brain Shift in Temporal Lobe Resection for Epilepsy Surgery
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2602.03785