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Bibliographic Details
Main Authors: Zhou, Junting, Chen, Jin, Hao, Linfeng, Cao, Denghui, Wang, Zheyu, Chen, Qiguang, Fu, Chaoyou, Chen, Jiaze, Wu, Yuchen, Zhang, Ge, Wang, Mingxuan, Huang, Wenhao, Yang, Tong
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2602.05857
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Table of Contents:
  • The rapid evolution of large language models (LLMs) has expanded their capabilities from basic dialogue to advanced scientific reasoning. However, existing benchmarks in biology often fail to assess a critical skill required of researchers: the ability to integrate experimental results with contextual knowledge to derive meaningful conclusions. To address this gap, we introduce BABE(Biology Arena BEnchmark), a comprehensive benchmark designed to evaluate the experimental reasoning capabilities of biological AI systems. BABE is uniquely constructed from peer-reviewed research papers and real-world biological studies, ensuring that tasks reflect the complexity and interdisciplinary nature of actual scientific inquiry. BABE challenges models to perform causal reasoning and cross-scale inference. Our benchmark provides a robust framework for assessing how well AI systems can reason like practicing scientists, offering a more authentic measure of their potential to contribute to biological research.