Multi-Scale Global-Instance Prompt Tuning for Continual Test-time Adaptation in Medical Image Segmentation
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arXiv
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| Autori principali: | , , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2026
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| _version_ | 1866918324655357952 |
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| author | Li, Lingrui Zhou, Yanfeng Pu, Nan Chen, Xin Zhong, Zhun |
| author_facet | Li, Lingrui Zhou, Yanfeng Pu, Nan Chen, Xin Zhong, Zhun |
| contents | Distribution shift is a common challenge in medical images obtained from different clinical centers, significantly hindering the deployment of pre-trained semantic segmentation models in real-world applications across multiple domains. Continual Test-Time Adaptation(CTTA) has emerged as a promising approach to address cross-domain shifts during continually evolving target domains. Most existing CTTA methods rely on incrementally updating model parameters, which inevitably suffer from error accumulation and catastrophic forgetting, especially in long-term adaptation. Recent prompt-tuning-based works have shown potential to mitigate the two issues above by updating only visual prompts. While these approaches have demonstrated promising performance, several limitations remain:1)lacking multi-scale prompt diversity, 2)inadequate incorporation of instance-specific knowledge, and 3)risk of privacy leakage. To overcome these limitations, we propose Multi-scale Global-Instance Prompt Tuning(MGIPT), to enhance scale diversity of prompts and capture both global- and instance-level knowledge for robust CTTA. Specifically, MGIPT consists of an Adaptive-scale Instance Prompt(AIP) and a Multi-scale Global-level Prompt(MGP). AIP dynamically learns lightweight and instance-specific prompts to mitigate error accumulation with adaptive optimal-scale selection mechanism. MGP captures domain-level knowledge across different scales to ensure robust adaptation with anti-forgetting capabilities. These complementary components are combined through a weighted ensemble approach, enabling effective dual-level adaptation that integrates both global and local information. Extensive experiments on medical image segmentation benchmarks demonstrate that our MGIPT outperforms state-of-the-art methods, achieving robust adaptation across continually changing target domains. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2602_05937 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Multi-Scale Global-Instance Prompt Tuning for Continual Test-time Adaptation in Medical Image Segmentation Li, Lingrui Zhou, Yanfeng Pu, Nan Chen, Xin Zhong, Zhun Computer Vision and Pattern Recognition Distribution shift is a common challenge in medical images obtained from different clinical centers, significantly hindering the deployment of pre-trained semantic segmentation models in real-world applications across multiple domains. Continual Test-Time Adaptation(CTTA) has emerged as a promising approach to address cross-domain shifts during continually evolving target domains. Most existing CTTA methods rely on incrementally updating model parameters, which inevitably suffer from error accumulation and catastrophic forgetting, especially in long-term adaptation. Recent prompt-tuning-based works have shown potential to mitigate the two issues above by updating only visual prompts. While these approaches have demonstrated promising performance, several limitations remain:1)lacking multi-scale prompt diversity, 2)inadequate incorporation of instance-specific knowledge, and 3)risk of privacy leakage. To overcome these limitations, we propose Multi-scale Global-Instance Prompt Tuning(MGIPT), to enhance scale diversity of prompts and capture both global- and instance-level knowledge for robust CTTA. Specifically, MGIPT consists of an Adaptive-scale Instance Prompt(AIP) and a Multi-scale Global-level Prompt(MGP). AIP dynamically learns lightweight and instance-specific prompts to mitigate error accumulation with adaptive optimal-scale selection mechanism. MGP captures domain-level knowledge across different scales to ensure robust adaptation with anti-forgetting capabilities. These complementary components are combined through a weighted ensemble approach, enabling effective dual-level adaptation that integrates both global and local information. Extensive experiments on medical image segmentation benchmarks demonstrate that our MGIPT outperforms state-of-the-art methods, achieving robust adaptation across continually changing target domains. |
| title | Multi-Scale Global-Instance Prompt Tuning for Continual Test-time Adaptation in Medical Image Segmentation |
| topic | Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2602.05937 |