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Main Authors: Lena, Chiara, Milesi, Davide, Casella, Alessandro, Carlini, Luca, Norton, Joseph C., Martin, James, Scaglioni, Bruno, Obstein, Keith L., De Sire, Roberto, Spadaccini, Marco, Hassan, Cesare, Valdastri, Pietro, De Momi, Elena
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2602.08397
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author Lena, Chiara
Milesi, Davide
Casella, Alessandro
Carlini, Luca
Norton, Joseph C.
Martin, James
Scaglioni, Bruno
Obstein, Keith L.
De Sire, Roberto
Spadaccini, Marco
Hassan, Cesare
Valdastri, Pietro
De Momi, Elena
author_facet Lena, Chiara
Milesi, Davide
Casella, Alessandro
Carlini, Luca
Norton, Joseph C.
Martin, James
Scaglioni, Bruno
Obstein, Keith L.
De Sire, Roberto
Spadaccini, Marco
Hassan, Cesare
Valdastri, Pietro
De Momi, Elena
contents Deep learning has the potential to improve colonoscopy by enabling 3D reconstruction of the colon, providing a comprehensive view of mucosal surfaces and lesions, and facilitating the identification of unexplored areas. However, the development of robust methods is limited by the scarcity of large-scale ground truth data. We propose RealSynCol, a highly realistic synthetic dataset designed to replicate the endoscopic environment. Colon geometries extracted from 10 CT scans were imported into a virtual environment that closely mimics intraoperative conditions and rendered with realistic vascular textures. The resulting dataset comprises 28\,130 frames, paired with ground truth depth maps, optical flow, 3D meshes, and camera trajectories. A benchmark study was conducted to evaluate the available synthetic colon datasets for the tasks of depth and pose estimation. Results demonstrate that the high realism and variability of RealSynCol significantly enhance generalization performance on clinical images, proving it to be a powerful tool for developing deep learning algorithms to support endoscopic diagnosis.
format Preprint
id arxiv_https___arxiv_org_abs_2602_08397
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle RealSynCol: a high-fidelity synthetic colon dataset for 3D reconstruction applications
Lena, Chiara
Milesi, Davide
Casella, Alessandro
Carlini, Luca
Norton, Joseph C.
Martin, James
Scaglioni, Bruno
Obstein, Keith L.
De Sire, Roberto
Spadaccini, Marco
Hassan, Cesare
Valdastri, Pietro
De Momi, Elena
Computer Vision and Pattern Recognition
Deep learning has the potential to improve colonoscopy by enabling 3D reconstruction of the colon, providing a comprehensive view of mucosal surfaces and lesions, and facilitating the identification of unexplored areas. However, the development of robust methods is limited by the scarcity of large-scale ground truth data. We propose RealSynCol, a highly realistic synthetic dataset designed to replicate the endoscopic environment. Colon geometries extracted from 10 CT scans were imported into a virtual environment that closely mimics intraoperative conditions and rendered with realistic vascular textures. The resulting dataset comprises 28\,130 frames, paired with ground truth depth maps, optical flow, 3D meshes, and camera trajectories. A benchmark study was conducted to evaluate the available synthetic colon datasets for the tasks of depth and pose estimation. Results demonstrate that the high realism and variability of RealSynCol significantly enhance generalization performance on clinical images, proving it to be a powerful tool for developing deep learning algorithms to support endoscopic diagnosis.
title RealSynCol: a high-fidelity synthetic colon dataset for 3D reconstruction applications
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2602.08397