A dialog between cell adhesion and topology at the core of morphogenesis
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arXiv
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| Auteurs principaux: | , , |
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| Format: | Preprint |
| Publié: |
2026
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| _version_ | 1866918468740186112 |
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| author | Aguirre-Tamaral, Adrian Floris, Elisa Corominas-Murtra, Bernat |
| author_facet | Aguirre-Tamaral, Adrian Floris, Elisa Corominas-Murtra, Bernat |
| contents | During the development of an organism, cells must coordinate and organize to generate the correct shape, structure, and spatial patterns of tissues and organs, a process known as morphogenesis. The morphogenesis of embryonic tissues is supported by multiple processes that induce the precise physical deformations required for tissues to ultimately form organs with complex geometries. Among the most active players shaping the morphogenetic path are fine-tuned changes in cell adhesion. We review here recent advances showing that changes on cell adhesion, a local, pair-wise property defined at the cell-cell contact level has important global consequences for embryonic tissue topology, being determinant in defining both the geometric and material properties of early embryo tissues. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2602_09867 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | A dialog between cell adhesion and topology at the core of morphogenesis Aguirre-Tamaral, Adrian Floris, Elisa Corominas-Murtra, Bernat Tissues and Organs Soft Condensed Matter Statistical Mechanics During the development of an organism, cells must coordinate and organize to generate the correct shape, structure, and spatial patterns of tissues and organs, a process known as morphogenesis. The morphogenesis of embryonic tissues is supported by multiple processes that induce the precise physical deformations required for tissues to ultimately form organs with complex geometries. Among the most active players shaping the morphogenetic path are fine-tuned changes in cell adhesion. We review here recent advances showing that changes on cell adhesion, a local, pair-wise property defined at the cell-cell contact level has important global consequences for embryonic tissue topology, being determinant in defining both the geometric and material properties of early embryo tissues. |
| title | A dialog between cell adhesion and topology at the core of morphogenesis |
| topic | Tissues and Organs Soft Condensed Matter Statistical Mechanics |
| url | https://arxiv.org/abs/2602.09867 |