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Hauptverfasser: Egunov, Aleksandr I., Tang, Hongmei, Saenz, Pablo E., Karnaushenko, Dmitriy D., Luo, Yumin, Zhong, Chao, Wang, Xinyu, Huang, Yang, Fedorov, Pavel, Merces, Leandro, Zhu, Minshen, Karnaushenko, Daniil, Oliver, Schmidt, G.
Format: Preprint
Veröffentlicht: 2026
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Online-Zugang:https://arxiv.org/abs/2602.09981
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author Egunov, Aleksandr I.
Tang, Hongmei
Saenz, Pablo E.
Karnaushenko, Dmitriy D.
Luo, Yumin
Zhong, Chao
Wang, Xinyu
Huang, Yang
Fedorov, Pavel
Merces, Leandro
Zhu, Minshen
Karnaushenko, Daniil
Oliver
Schmidt, G.
author_facet Egunov, Aleksandr I.
Tang, Hongmei
Saenz, Pablo E.
Karnaushenko, Dmitriy D.
Luo, Yumin
Zhong, Chao
Wang, Xinyu
Huang, Yang
Fedorov, Pavel
Merces, Leandro
Zhu, Minshen
Karnaushenko, Daniil
Oliver
Schmidt, G.
contents Thin-film self-assembly of three-dimensional (3D) microsystems presents a compelling route to integrate complex functionalities into ultra-compact volumes, yet strategies for incorporating tunable ion-conducting elements remain limited. Here, we introduce a strain-induced self assembly platform that transforms lithographically patterned multilayer thin films into functional 3D coaxial Swiss-roll microtubes with total active volumes below 1 uL. A key innovation is the monolithic integration of a chemically tunable polyimide proton-exchange membrane, enabling post-fabrication optimization of ionic transport that balances proton transport with mediator blocking. We further implement a dual-mode operational scheme that decouples microbial metabolism from electrochemical power generation, revealing biofouling, not chemical fouling or membrane degradation, as the dominant failure mechanism in conventional architectures. Critically, optimally treated polyimide membranes exhibit excellent recoverability after fouling, while cell-free mode operation maintains stable performance by physically excluding microorganisms from the microelectronic environment. This integrated bio-electronic microsystem achieves a volumetric power density of ~3.1 mW cm-3 within an ultra-compact footprint of 4.16 mm2. Our work establishes a scalable thin-film engineering approach to create tunable, 3D bioelectronic power sources for autonomous microsystems.
format Preprint
id arxiv_https___arxiv_org_abs_2602_09981
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Thin-Film-Engineered Self-Assembly of 3D Coaxial Microfluidics with a Tunable Polyimide Membrane for Bioelectronic Power
Egunov, Aleksandr I.
Tang, Hongmei
Saenz, Pablo E.
Karnaushenko, Dmitriy D.
Luo, Yumin
Zhong, Chao
Wang, Xinyu
Huang, Yang
Fedorov, Pavel
Merces, Leandro
Zhu, Minshen
Karnaushenko, Daniil
Oliver
Schmidt, G.
Applied Physics
Thin-film self-assembly of three-dimensional (3D) microsystems presents a compelling route to integrate complex functionalities into ultra-compact volumes, yet strategies for incorporating tunable ion-conducting elements remain limited. Here, we introduce a strain-induced self assembly platform that transforms lithographically patterned multilayer thin films into functional 3D coaxial Swiss-roll microtubes with total active volumes below 1 uL. A key innovation is the monolithic integration of a chemically tunable polyimide proton-exchange membrane, enabling post-fabrication optimization of ionic transport that balances proton transport with mediator blocking. We further implement a dual-mode operational scheme that decouples microbial metabolism from electrochemical power generation, revealing biofouling, not chemical fouling or membrane degradation, as the dominant failure mechanism in conventional architectures. Critically, optimally treated polyimide membranes exhibit excellent recoverability after fouling, while cell-free mode operation maintains stable performance by physically excluding microorganisms from the microelectronic environment. This integrated bio-electronic microsystem achieves a volumetric power density of ~3.1 mW cm-3 within an ultra-compact footprint of 4.16 mm2. Our work establishes a scalable thin-film engineering approach to create tunable, 3D bioelectronic power sources for autonomous microsystems.
title Thin-Film-Engineered Self-Assembly of 3D Coaxial Microfluidics with a Tunable Polyimide Membrane for Bioelectronic Power
topic Applied Physics
url https://arxiv.org/abs/2602.09981