Amortized Inference of Neuron Parameters on Analog Neuromorphic Hardware

Fuente: arXiv
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Auteurs principaux: Kaiser, Jakob, Müller, Eric, Schemmel, Johannes
Format: Preprint
Publié: 2026
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author Kaiser, Jakob
Müller, Eric
Schemmel, Johannes
author_facet Kaiser, Jakob
Müller, Eric
Schemmel, Johannes
contents Our work utilized a non-sequential simulation-based inference algorithm to provide an amortized neural density estimator, which approximates the posterior distribution for seven parameters of the adaptive exponential integrate-and-fire neuron model of the analog neuromorphic BrainScaleS-2 substrate. We constrained the large parameter space by training a binary classifier to predict parameter combinations yielding observations in regimes of interest, i.e. moderate spike counts. We compared two neural density estimators: one using handcrafted summary statistics and one using a summary network trained in combination with the neural density estimator. The summary network yielded a more focused posterior and generated posterior predictive traces that accurately captured the membrane potential dynamics. When using handcrafted summary statistics, posterior predictive traces match the included features but show deviations in the exact dynamics. The posteriors showed signs of bias and miscalibration but were still able to yield posterior predictive samples that were close to the target observations on which the posteriors were constrained. Our results validate amortized simulation-based inference as a tool for parameterizing analog neuron circuits.
format Preprint
id arxiv_https___arxiv_org_abs_2602_10763
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Amortized Inference of Neuron Parameters on Analog Neuromorphic Hardware
Kaiser, Jakob
Müller, Eric
Schemmel, Johannes
Neural and Evolutionary Computing
Our work utilized a non-sequential simulation-based inference algorithm to provide an amortized neural density estimator, which approximates the posterior distribution for seven parameters of the adaptive exponential integrate-and-fire neuron model of the analog neuromorphic BrainScaleS-2 substrate. We constrained the large parameter space by training a binary classifier to predict parameter combinations yielding observations in regimes of interest, i.e. moderate spike counts. We compared two neural density estimators: one using handcrafted summary statistics and one using a summary network trained in combination with the neural density estimator. The summary network yielded a more focused posterior and generated posterior predictive traces that accurately captured the membrane potential dynamics. When using handcrafted summary statistics, posterior predictive traces match the included features but show deviations in the exact dynamics. The posteriors showed signs of bias and miscalibration but were still able to yield posterior predictive samples that were close to the target observations on which the posteriors were constrained. Our results validate amortized simulation-based inference as a tool for parameterizing analog neuron circuits.
title Amortized Inference of Neuron Parameters on Analog Neuromorphic Hardware
topic Neural and Evolutionary Computing
url https://arxiv.org/abs/2602.10763