Reconstructing Network Outbreaks under Group Surveillance

Fuente: arXiv
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Autori principali: Mishra, Ritwick, Adiga, Abhijin, Vullikanti, Anil
Natura: Preprint
Pubblicazione: 2026
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author Mishra, Ritwick
Adiga, Abhijin
Vullikanti, Anil
author_facet Mishra, Ritwick
Adiga, Abhijin
Vullikanti, Anil
contents A key public health problem during an outbreak is to reconstruct the disease cascade from a partial set of confirmed infections. This has been studied extensively under the Maximum Likelihood Estimation (MLE) formulation, which reduces the problem to finding some type of Steiner subgraph on a network. Group surveillance like wastewater or aerosol monitoring is a form of mass/pooled testing where samples from multiple individuals are pooled together and tested once for all. While a single negative test clears multiple individuals, a positive test does not reveal the infected individuals in the test pool. We introduce the POOLCASCADEMLE problem in the setting of a network propagation process, where the goal is to find a MLE cascade subgraph which is consistent with the pooled test outcomes. Previous work on reconstruction assumes that the test results are of individuals, i.e., pools of size one, and requires a consistent cascade to connect the positive testing nodes. In POOLCASCADEMLE, a consistent cascade must choose at least one node in each positive pool, adding another combinatorial layer. We show that, under the Independent Cascade (IC) model, POOLCASCADEMLE is NP-hard, and present an approximation algorithm based on a reduction to the Group Steiner Tree problem. We also consider a one-hop version of this problem, in which the disease can spread for one time step after being seeded. We show that even this restricted version is NP-hard, and develop a method using linear programming relaxation and rounding. We evaluate the performance of our methods on real and synthetic contact networks, in terms of missing infection recovery and prevalence estimation. We find that our approach outperforms meaningful baselines which correspond to pools of size one and use state-of-the-art methods.
format Preprint
id arxiv_https___arxiv_org_abs_2602_11419
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Reconstructing Network Outbreaks under Group Surveillance
Mishra, Ritwick
Adiga, Abhijin
Vullikanti, Anil
Social and Information Networks
Multiagent Systems
A key public health problem during an outbreak is to reconstruct the disease cascade from a partial set of confirmed infections. This has been studied extensively under the Maximum Likelihood Estimation (MLE) formulation, which reduces the problem to finding some type of Steiner subgraph on a network. Group surveillance like wastewater or aerosol monitoring is a form of mass/pooled testing where samples from multiple individuals are pooled together and tested once for all. While a single negative test clears multiple individuals, a positive test does not reveal the infected individuals in the test pool. We introduce the POOLCASCADEMLE problem in the setting of a network propagation process, where the goal is to find a MLE cascade subgraph which is consistent with the pooled test outcomes. Previous work on reconstruction assumes that the test results are of individuals, i.e., pools of size one, and requires a consistent cascade to connect the positive testing nodes. In POOLCASCADEMLE, a consistent cascade must choose at least one node in each positive pool, adding another combinatorial layer. We show that, under the Independent Cascade (IC) model, POOLCASCADEMLE is NP-hard, and present an approximation algorithm based on a reduction to the Group Steiner Tree problem. We also consider a one-hop version of this problem, in which the disease can spread for one time step after being seeded. We show that even this restricted version is NP-hard, and develop a method using linear programming relaxation and rounding. We evaluate the performance of our methods on real and synthetic contact networks, in terms of missing infection recovery and prevalence estimation. We find that our approach outperforms meaningful baselines which correspond to pools of size one and use state-of-the-art methods.
title Reconstructing Network Outbreaks under Group Surveillance
topic Social and Information Networks
Multiagent Systems
url https://arxiv.org/abs/2602.11419