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Main Authors: Edwards, Connor W., Yang, Fengxu, Stracke, Konstantin, Evans, Jack D.
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2602.13725
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author Edwards, Connor W.
Yang, Fengxu
Stracke, Konstantin
Evans, Jack D.
author_facet Edwards, Connor W.
Yang, Fengxu
Stracke, Konstantin
Evans, Jack D.
contents Grand canonical Monte Carlo (GCMC) simulations are essential for screening metal-organic frameworks (MOFs) for gas adsorption, yet their accuracy is limited by underlying interatomic potentials. Universal machine-learned interatomic potentials (MLIPs), trained on diverse chemical datasets, promise zero-shot prediction without system-specific training. We introduce MLIP-MC, an open-source Python framework to conduct GCMC simulations with MLIPs, and use this framework to benchmark a series of universal models, including MACE-MP-0, ORB-v3, and fairchem ODAC, for CO2 adsorption on ZIF-8, ZIF-4, and Mg-MOF-74. All universal models exhibit systematic biases, consistently over- or underestimating adsorption energetics. Crucially, accuracy depends on training data composition: only models trained on MOF-adsorbate interactions achieve reasonable agreement with a density functional theory derived reference. Errors grow linearly with CO2 uptake, reflecting compounding inaccuracies in adsorbate-adsorbate interactions. Our results demonstrate that current universal MLIPs require finetuning for quantitative adsorption predictions and demonstrate the power of MLIP-MC to rapidly test models.
format Preprint
id arxiv_https___arxiv_org_abs_2602_13725
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle MLIP-MC: A Framework for Adsorption Simulations using Machine-Learned Interatomic Potentials
Edwards, Connor W.
Yang, Fengxu
Stracke, Konstantin
Evans, Jack D.
Materials Science
Grand canonical Monte Carlo (GCMC) simulations are essential for screening metal-organic frameworks (MOFs) for gas adsorption, yet their accuracy is limited by underlying interatomic potentials. Universal machine-learned interatomic potentials (MLIPs), trained on diverse chemical datasets, promise zero-shot prediction without system-specific training. We introduce MLIP-MC, an open-source Python framework to conduct GCMC simulations with MLIPs, and use this framework to benchmark a series of universal models, including MACE-MP-0, ORB-v3, and fairchem ODAC, for CO2 adsorption on ZIF-8, ZIF-4, and Mg-MOF-74. All universal models exhibit systematic biases, consistently over- or underestimating adsorption energetics. Crucially, accuracy depends on training data composition: only models trained on MOF-adsorbate interactions achieve reasonable agreement with a density functional theory derived reference. Errors grow linearly with CO2 uptake, reflecting compounding inaccuracies in adsorbate-adsorbate interactions. Our results demonstrate that current universal MLIPs require finetuning for quantitative adsorption predictions and demonstrate the power of MLIP-MC to rapidly test models.
title MLIP-MC: A Framework for Adsorption Simulations using Machine-Learned Interatomic Potentials
topic Materials Science
url https://arxiv.org/abs/2602.13725