Omni-iEEG: A Large-Scale, Comprehensive iEEG Dataset and Benchmark for Epilepsy Research

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Auteurs principaux: Duan, Chenda, Zhang, Yipeng, Kanai, Sotaro, Ding, Yuanyi, Daida, Atsuro, Yu, Pengyue, Zheng, Tiancheng, Kuroda, Naoto, Hussain, Shaun A., Asano, Eishi, Nariai, Hiroki, Roychowdhury, Vwani
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Publié: 2026
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author Duan, Chenda
Zhang, Yipeng
Kanai, Sotaro
Ding, Yuanyi
Daida, Atsuro
Yu, Pengyue
Zheng, Tiancheng
Kuroda, Naoto
Hussain, Shaun A.
Asano, Eishi
Nariai, Hiroki
Roychowdhury, Vwani
author_facet Duan, Chenda
Zhang, Yipeng
Kanai, Sotaro
Ding, Yuanyi
Daida, Atsuro
Yu, Pengyue
Zheng, Tiancheng
Kuroda, Naoto
Hussain, Shaun A.
Asano, Eishi
Nariai, Hiroki
Roychowdhury, Vwani
contents Epilepsy affects over 50 million people worldwide, and one-third of patients suffer drug-resistant seizures where surgery offers the best chance of seizure freedom. Accurate localization of the epileptogenic zone (EZ) relies on intracranial EEG (iEEG). Clinical workflows, however, remain constrained by labor-intensive manual review. At the same time, existing data-driven approaches are typically developed on single-center datasets that are inconsistent in format and metadata, lack standardized benchmarks, and rarely release pathological event annotations, creating barriers to reproducibility, cross-center validation, and clinical relevance. With extensive efforts to reconcile heterogeneous iEEG formats, metadata, and recordings across publicly available sources, we present $\textbf{Omni-iEEG}$, a large-scale, pre-surgical iEEG resource comprising $\textbf{302 patients}$ and $\textbf{178 hours}$ of high-resolution recordings. The dataset includes harmonized clinical metadata such as seizure onset zones, resections, and surgical outcomes, all validated by board-certified epileptologists. In addition, Omni-iEEG provides over 36K expert-validated annotations of pathological events, enabling robust biomarker studies. Omni-iEEG serves as a bridge between machine learning and epilepsy research. It defines clinically meaningful tasks with unified evaluation metrics grounded in clinical priors, enabling systematic evaluation of models in clinically relevant settings. Beyond benchmarking, we demonstrate the potential of end-to-end modeling on long iEEG segments and highlight the transferability of representations pretrained on non-neurophysiological domains. Together, these contributions establish Omni-iEEG as a foundation for reproducible, generalizable, and clinically translatable epilepsy research. The project page with dataset and code links is available at omni-ieeg.github.io/omni-ieeg.
format Preprint
id arxiv_https___arxiv_org_abs_2602_16072
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Omni-iEEG: A Large-Scale, Comprehensive iEEG Dataset and Benchmark for Epilepsy Research
Duan, Chenda
Zhang, Yipeng
Kanai, Sotaro
Ding, Yuanyi
Daida, Atsuro
Yu, Pengyue
Zheng, Tiancheng
Kuroda, Naoto
Hussain, Shaun A.
Asano, Eishi
Nariai, Hiroki
Roychowdhury, Vwani
Machine Learning
Artificial Intelligence
Neurons and Cognition
Epilepsy affects over 50 million people worldwide, and one-third of patients suffer drug-resistant seizures where surgery offers the best chance of seizure freedom. Accurate localization of the epileptogenic zone (EZ) relies on intracranial EEG (iEEG). Clinical workflows, however, remain constrained by labor-intensive manual review. At the same time, existing data-driven approaches are typically developed on single-center datasets that are inconsistent in format and metadata, lack standardized benchmarks, and rarely release pathological event annotations, creating barriers to reproducibility, cross-center validation, and clinical relevance. With extensive efforts to reconcile heterogeneous iEEG formats, metadata, and recordings across publicly available sources, we present $\textbf{Omni-iEEG}$, a large-scale, pre-surgical iEEG resource comprising $\textbf{302 patients}$ and $\textbf{178 hours}$ of high-resolution recordings. The dataset includes harmonized clinical metadata such as seizure onset zones, resections, and surgical outcomes, all validated by board-certified epileptologists. In addition, Omni-iEEG provides over 36K expert-validated annotations of pathological events, enabling robust biomarker studies. Omni-iEEG serves as a bridge between machine learning and epilepsy research. It defines clinically meaningful tasks with unified evaluation metrics grounded in clinical priors, enabling systematic evaluation of models in clinically relevant settings. Beyond benchmarking, we demonstrate the potential of end-to-end modeling on long iEEG segments and highlight the transferability of representations pretrained on non-neurophysiological domains. Together, these contributions establish Omni-iEEG as a foundation for reproducible, generalizable, and clinically translatable epilepsy research. The project page with dataset and code links is available at omni-ieeg.github.io/omni-ieeg.
title Omni-iEEG: A Large-Scale, Comprehensive iEEG Dataset and Benchmark for Epilepsy Research
topic Machine Learning
Artificial Intelligence
Neurons and Cognition
url https://arxiv.org/abs/2602.16072