Artefact-Aware Fungal Detection in Dermatophytosis: A Real-Time Transformer-Based Approach for KOH Microscopy

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Auteurs principaux: Gursoy, Rana, Yilmaz, Abdurrahim, Kizilyaprak, Baris, Caglar, Esmahan, Temelkuran, Burak, Uvet, Huseyin, Aksu, Ayse Esra Koku, Gencoglan, Gulsum
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Publié: 2026
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author Gursoy, Rana
Yilmaz, Abdurrahim
Kizilyaprak, Baris
Caglar, Esmahan
Temelkuran, Burak
Uvet, Huseyin
Aksu, Ayse Esra Koku
Gencoglan, Gulsum
author_facet Gursoy, Rana
Yilmaz, Abdurrahim
Kizilyaprak, Baris
Caglar, Esmahan
Temelkuran, Burak
Uvet, Huseyin
Aksu, Ayse Esra Koku
Gencoglan, Gulsum
contents Dermatophytosis is commonly assessed using potassium hydroxide (KOH) microscopy, yet accurate recognition of fungal hyphae is hindered by artefacts, heterogeneous keratin clearance, and notable inter-observer variability. This study presents a transformer-based detection framework using the RT-DETR model architecture to achieve precise, query-driven localization of fungal structures in high-resolution KOH images. A dataset of 2,540 routinely acquired microscopy images was manually annotated using a multi-class strategy to explicitly distinguish fungal elements from confounding artefacts. The model was trained with morphology-preserving augmentations to maintain the structural integrity of thin hyphae. Evaluation on an independent test set demonstrated robust object-level performance, with a recall of 0.9737, precision of 0.8043, and an AP@0.50 of 93.56%. When aggregated for image-level diagnosis, the model achieved 100% sensitivity and 98.8% accuracy, correctly identifying all positive cases without missing a single diagnosis. Qualitative outputs confirmed the robust localization of low-contrast hyphae even in artefact-rich fields. These results highlight that an artificial intelligence (AI) system can serve as a highly reliable, automated screening tool, effectively bridging the gap between image-level analysis and clinical decision-making in dermatomycology.
format Preprint
id arxiv_https___arxiv_org_abs_2602_19156
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Artefact-Aware Fungal Detection in Dermatophytosis: A Real-Time Transformer-Based Approach for KOH Microscopy
Gursoy, Rana
Yilmaz, Abdurrahim
Kizilyaprak, Baris
Caglar, Esmahan
Temelkuran, Burak
Uvet, Huseyin
Aksu, Ayse Esra Koku
Gencoglan, Gulsum
Computer Vision and Pattern Recognition
Artificial Intelligence
Dermatophytosis is commonly assessed using potassium hydroxide (KOH) microscopy, yet accurate recognition of fungal hyphae is hindered by artefacts, heterogeneous keratin clearance, and notable inter-observer variability. This study presents a transformer-based detection framework using the RT-DETR model architecture to achieve precise, query-driven localization of fungal structures in high-resolution KOH images. A dataset of 2,540 routinely acquired microscopy images was manually annotated using a multi-class strategy to explicitly distinguish fungal elements from confounding artefacts. The model was trained with morphology-preserving augmentations to maintain the structural integrity of thin hyphae. Evaluation on an independent test set demonstrated robust object-level performance, with a recall of 0.9737, precision of 0.8043, and an AP@0.50 of 93.56%. When aggregated for image-level diagnosis, the model achieved 100% sensitivity and 98.8% accuracy, correctly identifying all positive cases without missing a single diagnosis. Qualitative outputs confirmed the robust localization of low-contrast hyphae even in artefact-rich fields. These results highlight that an artificial intelligence (AI) system can serve as a highly reliable, automated screening tool, effectively bridging the gap between image-level analysis and clinical decision-making in dermatomycology.
title Artefact-Aware Fungal Detection in Dermatophytosis: A Real-Time Transformer-Based Approach for KOH Microscopy
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2602.19156