Towards Structure-Aware Surrogate Modeling: Explicit Region Interaction Improves Knee Contact Stress Prediction
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arXiv
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| Format: | Preprint |
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2026
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| _version_ | 1866912925913972736 |
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| author | Pan, Zhengye Zuo, Jianwei Luo, Jiajia |
| author_facet | Pan, Zhengye Zuo, Jianwei Luo, Jiajia |
| contents | Knee contact-stress hotspots are closely linked to meniscal/cartilage injury risk. Still, high-fidelity subject-specific FEA is too computationally expensive for large-cohort, multi-condition, near-real-time use. Existing MeshGraphNet-style surrogates mainly rely on stacked local message passing, which is often insufficient for modeling long-range dependencies and limits interpretability. This study benchmarked a deep-stacked baseline model against three explicit region-interaction architectures. Using a 90° change-of-direction task and a strict cross-subject evaluation framework, we assessed whole-field error, peak stress fidelity, and hotspot spatial consistency under matched computational budgets. Region-interaction models significantly reduced whole-field nodal stress errors compared to the purely stacked baseline. Crucially, they achieved markedly higher accuracy in reconstructing the high-stress tail and demonstrated superior spatial consistency and temporal robustness in localizing high-risk stress hotspots. Explicit region-level interaction provides a more structure-aligned surrogate modeling paradigm for knee contact mechanics and yields stronger risk-relevant stress phenotype recovery under comparable computational budgets, while supporting more interpretable injury-risk assessment. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2602_21488 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Towards Structure-Aware Surrogate Modeling: Explicit Region Interaction Improves Knee Contact Stress Prediction Pan, Zhengye Zuo, Jianwei Luo, Jiajia Tissues and Organs Knee contact-stress hotspots are closely linked to meniscal/cartilage injury risk. Still, high-fidelity subject-specific FEA is too computationally expensive for large-cohort, multi-condition, near-real-time use. Existing MeshGraphNet-style surrogates mainly rely on stacked local message passing, which is often insufficient for modeling long-range dependencies and limits interpretability. This study benchmarked a deep-stacked baseline model against three explicit region-interaction architectures. Using a 90° change-of-direction task and a strict cross-subject evaluation framework, we assessed whole-field error, peak stress fidelity, and hotspot spatial consistency under matched computational budgets. Region-interaction models significantly reduced whole-field nodal stress errors compared to the purely stacked baseline. Crucially, they achieved markedly higher accuracy in reconstructing the high-stress tail and demonstrated superior spatial consistency and temporal robustness in localizing high-risk stress hotspots. Explicit region-level interaction provides a more structure-aligned surrogate modeling paradigm for knee contact mechanics and yields stronger risk-relevant stress phenotype recovery under comparable computational budgets, while supporting more interpretable injury-risk assessment. |
| title | Towards Structure-Aware Surrogate Modeling: Explicit Region Interaction Improves Knee Contact Stress Prediction |
| topic | Tissues and Organs |
| url | https://arxiv.org/abs/2602.21488 |