Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Preprint |
| Pubblicazione: |
2026
|
| Soggetti: | |
| Accesso online: | https://arxiv.org/abs/2602.23492 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
Sommario:
- We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic medical record notes for patients treated with lung stereotactic body radiotherapy (SBRT) at our institution from January 2017 through December 2023. Using the Llama 3.3-70-B-Instruct LLM, we engineered prompts to extract four clinical endpoints from each radiology report: locoregional progression, distant progression, radiation-induced fibrosis, and radiation-induced rib fractures. Progression endpoints were classified as yes, no, or maybe, while fibrosis and rib fractures were binary (yes or no). Ground truth labels were defined using two-grader consensus for the 60-note training set, used for prompt development, and a three-grader majority vote for the 100-note test set. LLM performance was evaluated using sensitivity, specificity, and accuracy. As detailed by our evaluation metrics, the strong performance of our methods demonstrates the viability of using prompt-engineered LLMs to extract radiation-toxicities and progression classification from radiology reports.