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Bibliographic Details
Main Authors: Kalaycioglu, S., Hong, C., Zhu, M., Xie, H.
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2603.00161
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author Kalaycioglu, S.
Hong, C.
Zhu, M.
Xie, H.
author_facet Kalaycioglu, S.
Hong, C.
Zhu, M.
Xie, H.
contents Early ophthalmic screening in low-resource and remote settings is constrained by access to specialized equipment and trained practitioners. We present SKINOPATHY AI, a smartphone-first web application that delivers five complementary, explainable screening modules entirely through commodity mobile hardware: (1) redness quantification via LAB a* color-space normalization; (2) blink-rate estimation using MediaPipe FaceMesh Eye Aspect Ratio (EAR) with adaptive thresholding; (3) pupil light reflex characterization through Pupil-to-Iris Ratio (PIR) time-series analysis; (4) scleral color indexing foricterus and anemia proxies via LAB/HSV statistics; and (5) iris-landmark-calibrated lesion encroachment measurement with millimeter-scale estimates and longitudinal trend tracking. The system is implemented as a React/FastAPI stack with OpenCV and MediaPipe, MongoDB-backed session persistence, and PDF report generation. All algorithms are fully deterministic, privacy-preserving, and designed for non-diagnostic consumer triage. We detail system architecture, algorithm design, evaluation methodology, clinical context, and ethical boundaries of the platform. SKINOPATHY AI demonstrates that multi-signal ophthalmic screening is feasible on unmodified smartphones without cloud-based AI inference, providing a foundation for future clinically validated mobile ophthalmoscopy tools.
format Preprint
id arxiv_https___arxiv_org_abs_2603_00161
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle SKINOPATHY AI: Smartphone-Based Ophthalmic Screening and Longitudinal Tracking Using Lightweight Computer Vision
Kalaycioglu, S.
Hong, C.
Zhu, M.
Xie, H.
Computer Vision and Pattern Recognition
Machine Learning
Early ophthalmic screening in low-resource and remote settings is constrained by access to specialized equipment and trained practitioners. We present SKINOPATHY AI, a smartphone-first web application that delivers five complementary, explainable screening modules entirely through commodity mobile hardware: (1) redness quantification via LAB a* color-space normalization; (2) blink-rate estimation using MediaPipe FaceMesh Eye Aspect Ratio (EAR) with adaptive thresholding; (3) pupil light reflex characterization through Pupil-to-Iris Ratio (PIR) time-series analysis; (4) scleral color indexing foricterus and anemia proxies via LAB/HSV statistics; and (5) iris-landmark-calibrated lesion encroachment measurement with millimeter-scale estimates and longitudinal trend tracking. The system is implemented as a React/FastAPI stack with OpenCV and MediaPipe, MongoDB-backed session persistence, and PDF report generation. All algorithms are fully deterministic, privacy-preserving, and designed for non-diagnostic consumer triage. We detail system architecture, algorithm design, evaluation methodology, clinical context, and ethical boundaries of the platform. SKINOPATHY AI demonstrates that multi-signal ophthalmic screening is feasible on unmodified smartphones without cloud-based AI inference, providing a foundation for future clinically validated mobile ophthalmoscopy tools.
title SKINOPATHY AI: Smartphone-Based Ophthalmic Screening and Longitudinal Tracking Using Lightweight Computer Vision
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2603.00161