How Well Do Multimodal Models Reason on ECG Signals?

Fuente: arXiv
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Main Authors: Xu, Maxwell A., Haresamudram, Harish, Liu, Catherine W., Langer, Patrick, Pradeepkumar, Jathurshan, Mao, Wanting, Ferns, Sunita J., Verma, Aradhana, Sun, Jimeng, Schmiedmayer, Paul, Liu, Xin, McDuff, Daniel, Fox, Emily B., Rehg, James M.
Format: Preprint
Published: 2026
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author Xu, Maxwell A.
Haresamudram, Harish
Liu, Catherine W.
Langer, Patrick
Pradeepkumar, Jathurshan
Mao, Wanting
Ferns, Sunita J.
Verma, Aradhana
Sun, Jimeng
Schmiedmayer, Paul
Liu, Xin
McDuff, Daniel
Fox, Emily B.
Rehg, James M.
author_facet Xu, Maxwell A.
Haresamudram, Harish
Liu, Catherine W.
Langer, Patrick
Pradeepkumar, Jathurshan
Mao, Wanting
Ferns, Sunita J.
Verma, Aradhana
Sun, Jimeng
Schmiedmayer, Paul
Liu, Xin
McDuff, Daniel
Fox, Emily B.
Rehg, James M.
contents While multimodal large language models offer a promising solution to the "black box" nature of health AI by generating interpretable reasoning traces, verifying the validity of these traces remains a critical challenge. Existing evaluation methods are either unscalable, relying on manual clinician review, or superficial, utilizing proxy metrics (e.g. QA) that fail to capture the semantic correctness of clinical logic. In this work, we introduce a reproducible framework for evaluating reasoning in ECG signals. We propose decomposing reasoning into two distinct, components: (i) Perception, the accurate identification of patterns within the raw signal, and (ii) Deduction, the logical application of domain knowledge to those patterns. To evaluate Perception, we employ an agentic framework that generates code to empirically verify the temporal structures described in the reasoning trace. To evaluate Deduction, we measure the alignment of the model's logic against a structured database of established clinical criteria in a retrieval-based approach. This dual-verification method enables the scalable assessment of "true" reasoning capabilities.
format Preprint
id arxiv_https___arxiv_org_abs_2603_00312
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle How Well Do Multimodal Models Reason on ECG Signals?
Xu, Maxwell A.
Haresamudram, Harish
Liu, Catherine W.
Langer, Patrick
Pradeepkumar, Jathurshan
Mao, Wanting
Ferns, Sunita J.
Verma, Aradhana
Sun, Jimeng
Schmiedmayer, Paul
Liu, Xin
McDuff, Daniel
Fox, Emily B.
Rehg, James M.
Artificial Intelligence
Machine Learning
While multimodal large language models offer a promising solution to the "black box" nature of health AI by generating interpretable reasoning traces, verifying the validity of these traces remains a critical challenge. Existing evaluation methods are either unscalable, relying on manual clinician review, or superficial, utilizing proxy metrics (e.g. QA) that fail to capture the semantic correctness of clinical logic. In this work, we introduce a reproducible framework for evaluating reasoning in ECG signals. We propose decomposing reasoning into two distinct, components: (i) Perception, the accurate identification of patterns within the raw signal, and (ii) Deduction, the logical application of domain knowledge to those patterns. To evaluate Perception, we employ an agentic framework that generates code to empirically verify the temporal structures described in the reasoning trace. To evaluate Deduction, we measure the alignment of the model's logic against a structured database of established clinical criteria in a retrieval-based approach. This dual-verification method enables the scalable assessment of "true" reasoning capabilities.
title How Well Do Multimodal Models Reason on ECG Signals?
topic Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2603.00312