Solving a Nonlinear Blind Inverse Problem for Tagged MRI with Physics and Deep Generative Priors

Fuente: arXiv
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Autores principales: Bian, Zhangxing, Wei, Shuwen, Remedios, Samuel W., Chen, Junyu, Carass, Aaron, Dewey, Blake E., Prince, Jerry L.
Formato: Preprint
Publicado: 2026
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author Bian, Zhangxing
Wei, Shuwen
Remedios, Samuel W.
Chen, Junyu
Carass, Aaron
Dewey, Blake E.
Prince, Jerry L.
author_facet Bian, Zhangxing
Wei, Shuwen
Remedios, Samuel W.
Chen, Junyu
Carass, Aaron
Dewey, Blake E.
Prince, Jerry L.
contents Tagged MRI enables tracking internal tissue motion non-invasively. It encodes motion by modulating anatomy with periodic tags, which deform along with tissue. However, the entanglement between anatomy, tags and motion poses significant challenges for post-processing. The existence of tags and imaging blur hinders downstream tasks such as segmenting anatomy. Tag fading, due to T1-relaxation, disrupts the brightness constancy assumption for motion tracking. For decades, these challenges have been handled in isolation and sub-optimally. In contrast, we introduce a blind and nonlinear inverse framework for tagged MRI that, for the first time, unifies these tasks: anatomical image recovery, high-resolution cine image synthesis, and motion estimation. At its core, the synergy of MR physics and generative priors enables us to blindly estimate the unknown forward imaging models and high-resolution underlying anatomy, while simultaneously tracking 3D diffeomorphic Lagrangian motion over time. Experiments on tagged brain MRI demonstrate that our approach yields high-resolution anatomy images, cine images, and more accurate motion than specialized methods.
format Preprint
id arxiv_https___arxiv_org_abs_2603_00882
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Solving a Nonlinear Blind Inverse Problem for Tagged MRI with Physics and Deep Generative Priors
Bian, Zhangxing
Wei, Shuwen
Remedios, Samuel W.
Chen, Junyu
Carass, Aaron
Dewey, Blake E.
Prince, Jerry L.
Image and Video Processing
Computer Vision and Pattern Recognition
Signal Processing
Tagged MRI enables tracking internal tissue motion non-invasively. It encodes motion by modulating anatomy with periodic tags, which deform along with tissue. However, the entanglement between anatomy, tags and motion poses significant challenges for post-processing. The existence of tags and imaging blur hinders downstream tasks such as segmenting anatomy. Tag fading, due to T1-relaxation, disrupts the brightness constancy assumption for motion tracking. For decades, these challenges have been handled in isolation and sub-optimally. In contrast, we introduce a blind and nonlinear inverse framework for tagged MRI that, for the first time, unifies these tasks: anatomical image recovery, high-resolution cine image synthesis, and motion estimation. At its core, the synergy of MR physics and generative priors enables us to blindly estimate the unknown forward imaging models and high-resolution underlying anatomy, while simultaneously tracking 3D diffeomorphic Lagrangian motion over time. Experiments on tagged brain MRI demonstrate that our approach yields high-resolution anatomy images, cine images, and more accurate motion than specialized methods.
title Solving a Nonlinear Blind Inverse Problem for Tagged MRI with Physics and Deep Generative Priors
topic Image and Video Processing
Computer Vision and Pattern Recognition
Signal Processing
url https://arxiv.org/abs/2603.00882