Wavelength and Polarization Multiplexed Nonlocal Metasurface for Quantitative Phase Microscopy

Fuente: arXiv
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Autori principali: Wang, Haiwei, Ma, Shikun, Sulejman, Shaban B., Priscilla, Niken, Lee, Wendy S. L., Elango, Peter Francis Matthew, Wesemann, Lukas, Hinde, Elizabeth, Roberts, Ann
Natura: Preprint
Pubblicazione: 2026
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author Wang, Haiwei
Ma, Shikun
Sulejman, Shaban B.
Priscilla, Niken
Lee, Wendy S. L.
Elango, Peter Francis Matthew
Wesemann, Lukas
Hinde, Elizabeth
Roberts, Ann
author_facet Wang, Haiwei
Ma, Shikun
Sulejman, Shaban B.
Priscilla, Niken
Lee, Wendy S. L.
Elango, Peter Francis Matthew
Wesemann, Lukas
Hinde, Elizabeth
Roberts, Ann
contents Imaging transparent samples remains an ongoing challenge in the study of unstained biological cells and material samples. Widely used methods trade off system complexity, cost and bulk, computational efficiency and information content. Here we demonstrate the use of a nonlocal metasurface located in the object plane for obtaining single-shot, low-noise differential phase contrast images visualising phase gradients along orthogonal directions in a sample obtained at wavelengths of 613 nm and 656 nm. Furthermore, we show that these images are sufficient to calculate the quantitative phase introduced into the transmitted optical field by the sample. We find that the recovered phase of an optical field generated by a spatial light modulator is in good agreement with specified values. We also present information-rich differential phase contrast images of unstained HeLa cells with the recovered phase excursion values consistent with the literature. Our results demonstrate the potential for metasurfaces as a platform for extracting information from an optical field for use in next-generation compact imaging systems with applications in medical diagnostics, biotechnology, and materials science.
format Preprint
id arxiv_https___arxiv_org_abs_2603_02446
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Wavelength and Polarization Multiplexed Nonlocal Metasurface for Quantitative Phase Microscopy
Wang, Haiwei
Ma, Shikun
Sulejman, Shaban B.
Priscilla, Niken
Lee, Wendy S. L.
Elango, Peter Francis Matthew
Wesemann, Lukas
Hinde, Elizabeth
Roberts, Ann
Optics
Imaging transparent samples remains an ongoing challenge in the study of unstained biological cells and material samples. Widely used methods trade off system complexity, cost and bulk, computational efficiency and information content. Here we demonstrate the use of a nonlocal metasurface located in the object plane for obtaining single-shot, low-noise differential phase contrast images visualising phase gradients along orthogonal directions in a sample obtained at wavelengths of 613 nm and 656 nm. Furthermore, we show that these images are sufficient to calculate the quantitative phase introduced into the transmitted optical field by the sample. We find that the recovered phase of an optical field generated by a spatial light modulator is in good agreement with specified values. We also present information-rich differential phase contrast images of unstained HeLa cells with the recovered phase excursion values consistent with the literature. Our results demonstrate the potential for metasurfaces as a platform for extracting information from an optical field for use in next-generation compact imaging systems with applications in medical diagnostics, biotechnology, and materials science.
title Wavelength and Polarization Multiplexed Nonlocal Metasurface for Quantitative Phase Microscopy
topic Optics
url https://arxiv.org/abs/2603.02446