Deep Learning-based Assessment of the Relation Between the Third Molar and Mandibular Canal on Panoramic Radiographs using Local, Centralized, and Federated Learning

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Main Authors: Rubak, Johan Andreas Balle, Haghighat, Sara, Jain, Sanyam, Aldesoki, Mostafa, Chaurasia, Akhilanand, Ehsani, Sarah Sadat, Ghanatkaman, Faezeh Dehghan, Ghazali, Ahmad Badruddin, Issa, Julien, Khalil, Basel, Ramani, Rishi, Pauwels, Ruben
Format: Preprint
Published: 2026
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author Rubak, Johan Andreas Balle
Haghighat, Sara
Jain, Sanyam
Aldesoki, Mostafa
Chaurasia, Akhilanand
Ehsani, Sarah Sadat
Ghanatkaman, Faezeh Dehghan
Ghazali, Ahmad Badruddin
Issa, Julien
Khalil, Basel
Ramani, Rishi
Pauwels, Ruben
author_facet Rubak, Johan Andreas Balle
Haghighat, Sara
Jain, Sanyam
Aldesoki, Mostafa
Chaurasia, Akhilanand
Ehsani, Sarah Sadat
Ghanatkaman, Faezeh Dehghan
Ghazali, Ahmad Badruddin
Issa, Julien
Khalil, Basel
Ramani, Rishi
Pauwels, Ruben
contents Impaction of the mandibular third molar in proximity to the mandibular canal increases the risk of inferior alveolar nerve injury. Panoramic radiography is routinely used to assess this relationship. Automated classification of molar-canal overlap could support clinical triage and reduce unnecessary CBCT referrals, while federated learning (FL) enables multi-center collaboration without sharing patient data. We compared Local Learning (LL), FL, and Centralized Learning (CL) for binary overlap/no-overlap classification on cropped panoramic radiographs partitioned across eight independent labelers. A pretrained ResNet-34 was trained under each paradigm and evaluated using per-client metrics with locally optimized thresholds and pooled test performance with a global threshold. Performance was assessed using area under the receiver operating characteristic curve (AUC) and threshold-based metrics, alongside training dynamics, Grad-CAM visualizations, and server-side aggregate monitoring signals. On the test set, CL achieved the highest performance (AUC 0.831; accuracy = 0.782), FL showed intermediate performance (AUC 0.757; accuracy = 0.703), and LL generalized poorly across clients (AUC range = 0.619-0.734; mean = 0.672). Training curves suggested overfitting, particularly in LL models, and Grad-CAM indicated more anatomically focused attention in CL and FL. Overall, centralized training provided the strongest performance, while FL offers a privacy-preserving alternative that outperforms LL.
format Preprint
id arxiv_https___arxiv_org_abs_2603_11850
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Deep Learning-based Assessment of the Relation Between the Third Molar and Mandibular Canal on Panoramic Radiographs using Local, Centralized, and Federated Learning
Rubak, Johan Andreas Balle
Haghighat, Sara
Jain, Sanyam
Aldesoki, Mostafa
Chaurasia, Akhilanand
Ehsani, Sarah Sadat
Ghanatkaman, Faezeh Dehghan
Ghazali, Ahmad Badruddin
Issa, Julien
Khalil, Basel
Ramani, Rishi
Pauwels, Ruben
Image and Video Processing
Computer Vision and Pattern Recognition
Distributed, Parallel, and Cluster Computing
Impaction of the mandibular third molar in proximity to the mandibular canal increases the risk of inferior alveolar nerve injury. Panoramic radiography is routinely used to assess this relationship. Automated classification of molar-canal overlap could support clinical triage and reduce unnecessary CBCT referrals, while federated learning (FL) enables multi-center collaboration without sharing patient data. We compared Local Learning (LL), FL, and Centralized Learning (CL) for binary overlap/no-overlap classification on cropped panoramic radiographs partitioned across eight independent labelers. A pretrained ResNet-34 was trained under each paradigm and evaluated using per-client metrics with locally optimized thresholds and pooled test performance with a global threshold. Performance was assessed using area under the receiver operating characteristic curve (AUC) and threshold-based metrics, alongside training dynamics, Grad-CAM visualizations, and server-side aggregate monitoring signals. On the test set, CL achieved the highest performance (AUC 0.831; accuracy = 0.782), FL showed intermediate performance (AUC 0.757; accuracy = 0.703), and LL generalized poorly across clients (AUC range = 0.619-0.734; mean = 0.672). Training curves suggested overfitting, particularly in LL models, and Grad-CAM indicated more anatomically focused attention in CL and FL. Overall, centralized training provided the strongest performance, while FL offers a privacy-preserving alternative that outperforms LL.
title Deep Learning-based Assessment of the Relation Between the Third Molar and Mandibular Canal on Panoramic Radiographs using Local, Centralized, and Federated Learning
topic Image and Video Processing
Computer Vision and Pattern Recognition
Distributed, Parallel, and Cluster Computing
url https://arxiv.org/abs/2603.11850