Tensorial Reduced-Order Models for Parametric Coupled Reaction-Diffusion Systems: Application to Brain Tumor Growth Modeling

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Main Authors: Islam, Asikul, Mizan, Md Rezwan Bin, Olshanskii, Maxim, Mang, Andreas
Format: Preprint
Published: 2026
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author Islam, Asikul
Mizan, Md Rezwan Bin
Olshanskii, Maxim
Mang, Andreas
author_facet Islam, Asikul
Mizan, Md Rezwan Bin
Olshanskii, Maxim
Mang, Andreas
contents We construct efficient surrogate models for parametric forward operators arising in brain tumor growth simulations, governed by coupled semilinear parabolic reaction-diffusion systems on heterogeneous two- and three-dimensional domains. We consider two models of increasing complexity: a scalar single-species formulation and a six-state, nine-parameter multi-species go-or-grow model. The governing equations are discretized using a finite volume method and integrated in time via an operator-splitting strategy. We develop tensorial reduced-order model (TROM) surrogates based on the Higher-Order Singular Value Decomposition in Tucker format and the Tensor Train decomposition, each in intrusive and non-intrusive variants. The models are compared against a classical proper orthogonal decomposition (POD) ROM baseline. Numerical experiments with up to $m=9$ model parameters demonstrate speedups of $85\times$-$120\times$ relative to the full-order solver while maintaining excellent accuracy, establishing tensorial surrogates as a rigorous and efficient computational foundation for many-query workflows.
format Preprint
id arxiv_https___arxiv_org_abs_2603_14101
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Tensorial Reduced-Order Models for Parametric Coupled Reaction-Diffusion Systems: Application to Brain Tumor Growth Modeling
Islam, Asikul
Mizan, Md Rezwan Bin
Olshanskii, Maxim
Mang, Andreas
Numerical Analysis
15A69, 65D15, 65M08, 35K57, 35K58
We construct efficient surrogate models for parametric forward operators arising in brain tumor growth simulations, governed by coupled semilinear parabolic reaction-diffusion systems on heterogeneous two- and three-dimensional domains. We consider two models of increasing complexity: a scalar single-species formulation and a six-state, nine-parameter multi-species go-or-grow model. The governing equations are discretized using a finite volume method and integrated in time via an operator-splitting strategy. We develop tensorial reduced-order model (TROM) surrogates based on the Higher-Order Singular Value Decomposition in Tucker format and the Tensor Train decomposition, each in intrusive and non-intrusive variants. The models are compared against a classical proper orthogonal decomposition (POD) ROM baseline. Numerical experiments with up to $m=9$ model parameters demonstrate speedups of $85\times$-$120\times$ relative to the full-order solver while maintaining excellent accuracy, establishing tensorial surrogates as a rigorous and efficient computational foundation for many-query workflows.
title Tensorial Reduced-Order Models for Parametric Coupled Reaction-Diffusion Systems: Application to Brain Tumor Growth Modeling
topic Numerical Analysis
15A69, 65D15, 65M08, 35K57, 35K58
url https://arxiv.org/abs/2603.14101