ES-Merging: Biological MLLM Merging via Embedding Space Signals
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arXiv
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| Format: | Preprint |
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2026
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| _version_ | 1866917551915663360 |
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| author | Lee, Wonbin Kim, Dongki Hwang, Sung Ju |
| author_facet | Lee, Wonbin Kim, Dongki Hwang, Sung Ju |
| contents | Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal scientific problems. While model merging is an efficient method to combine the different modalities into a unified MLLM, existing methods rely on input-agnostic parameter space heuristics that fail to faithfully capture modality specialization. To overcome this limitation, we propose the Embedding-Signal-based MLLM Merging (ES-Merging), a framework that estimates merging coefficients from embedding space signals, moving the merging paradigm from the parameter signals to the embedding signals. ES-Merging exploits coarse-grained and fine-grained signals from embedding space to estimate the layer-wise and element-wise merging coefficients, respectively, which are jointly combined for complementary coefficient estimation. Through extensive experiments, we demonstrate that ES-Merging outperforms existing merging methods not only on the cross-modal reasoning but also on the single-modal knowledge preservation, establishing that embedding space signals provide a principled and effective foundation for MLLM merging. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2603_14405 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | ES-Merging: Biological MLLM Merging via Embedding Space Signals Lee, Wonbin Kim, Dongki Hwang, Sung Ju Machine Learning Artificial Intelligence Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal scientific problems. While model merging is an efficient method to combine the different modalities into a unified MLLM, existing methods rely on input-agnostic parameter space heuristics that fail to faithfully capture modality specialization. To overcome this limitation, we propose the Embedding-Signal-based MLLM Merging (ES-Merging), a framework that estimates merging coefficients from embedding space signals, moving the merging paradigm from the parameter signals to the embedding signals. ES-Merging exploits coarse-grained and fine-grained signals from embedding space to estimate the layer-wise and element-wise merging coefficients, respectively, which are jointly combined for complementary coefficient estimation. Through extensive experiments, we demonstrate that ES-Merging outperforms existing merging methods not only on the cross-modal reasoning but also on the single-modal knowledge preservation, establishing that embedding space signals provide a principled and effective foundation for MLLM merging. |
| title | ES-Merging: Biological MLLM Merging via Embedding Space Signals |
| topic | Machine Learning Artificial Intelligence |
| url | https://arxiv.org/abs/2603.14405 |