Time reversal breaking of colloidal particles in cells

Fuente: arXiv
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Main Authors: Knotz, Gabriel, Muenker, Till M., Betz, Timo, Krüger, Matthias
Format: Preprint
Published: 2026
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author Knotz, Gabriel
Muenker, Till M.
Betz, Timo
Krüger, Matthias
author_facet Knotz, Gabriel
Muenker, Till M.
Betz, Timo
Krüger, Matthias
contents We investigate signatures of broken time reversal symmetry in stochastic trajectory data, employing the previously introduced three point correlation called mean back relaxation. We specifically investigate data from a simple driven model, as well as from colloidal particles within living or passivated biological cells. Both in the model as well as in cell data, MBR detects broken time reversal symmetry, and furthermore, allows to determine relevant time and length scales of activity. For the cells, we show, by applying various drugs, that it is predominantly the presence of microtubules which is needed for a time reversal symmetry breaking. We employ a bound for entropy production, finding that it is in striking relation to previously determined active energies that quantify violation of the fluctuation dissipation theorem.
format Preprint
id arxiv_https___arxiv_org_abs_2603_16517
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Time reversal breaking of colloidal particles in cells
Knotz, Gabriel
Muenker, Till M.
Betz, Timo
Krüger, Matthias
Soft Condensed Matter
Statistical Mechanics
Biological Physics
We investigate signatures of broken time reversal symmetry in stochastic trajectory data, employing the previously introduced three point correlation called mean back relaxation. We specifically investigate data from a simple driven model, as well as from colloidal particles within living or passivated biological cells. Both in the model as well as in cell data, MBR detects broken time reversal symmetry, and furthermore, allows to determine relevant time and length scales of activity. For the cells, we show, by applying various drugs, that it is predominantly the presence of microtubules which is needed for a time reversal symmetry breaking. We employ a bound for entropy production, finding that it is in striking relation to previously determined active energies that quantify violation of the fluctuation dissipation theorem.
title Time reversal breaking of colloidal particles in cells
topic Soft Condensed Matter
Statistical Mechanics
Biological Physics
url https://arxiv.org/abs/2603.16517