Age-dependent distribution of officially reported cases of vector-borne infections

Fuente: arXiv
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Auteurs principaux: Coutinho, Francisco Antonio Bezerra, Amaku, Marcos, Kallas, Esper Georges, Massad, Eduardo
Format: Preprint
Publié: 2026
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author Coutinho, Francisco Antonio Bezerra
Amaku, Marcos
Kallas, Esper Georges
Massad, Eduardo
author_facet Coutinho, Francisco Antonio Bezerra
Amaku, Marcos
Kallas, Esper Georges
Massad, Eduardo
contents OBJECTIVE: To propose a new approach to analyze the age-distribution of reported cases for vector-transmitted infections. METHODS: Using officially reported number of cases of dengue, Zika, chikungunya, malaria and leishmaniasis for distinct geographical areas, in different periods. Data were treated in special but well-known procedure, transforming the raw data into a density age-dependent distribution and fitting a special continuous function to it. RESULTS: We found that the proportion of age-dependent cases with respect to the total number of cases in a given year (or any transmission season) is probably determined by the ecological interactions between vectors and hosts. The age-distribution of the proportion of cases for the three Aedes-related infections are essentially the same independently of the magnitude of the outbreak and the geographical region considered. On the other hand, for the infections transmitted by other vectors, the age-distributions of the proportion of cases are entirely different. CONCLUSIONS: During specific outbreaks, the ratio between the age distribution of the proportion of officially reported cases and the total number of cases for Aedes transmitted infections such as dengue, chikungunya and zika is independent of the size of the outbreak, the size of the studied population, the period when the outbreak occurs; and the geographical region considered. Our results also suggest that the age-distribution of cases is mainly due to the interaction between vectors and their hosts.
format Preprint
id arxiv_https___arxiv_org_abs_2603_16773
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Age-dependent distribution of officially reported cases of vector-borne infections
Coutinho, Francisco Antonio Bezerra
Amaku, Marcos
Kallas, Esper Georges
Massad, Eduardo
Populations and Evolution
OBJECTIVE: To propose a new approach to analyze the age-distribution of reported cases for vector-transmitted infections. METHODS: Using officially reported number of cases of dengue, Zika, chikungunya, malaria and leishmaniasis for distinct geographical areas, in different periods. Data were treated in special but well-known procedure, transforming the raw data into a density age-dependent distribution and fitting a special continuous function to it. RESULTS: We found that the proportion of age-dependent cases with respect to the total number of cases in a given year (or any transmission season) is probably determined by the ecological interactions between vectors and hosts. The age-distribution of the proportion of cases for the three Aedes-related infections are essentially the same independently of the magnitude of the outbreak and the geographical region considered. On the other hand, for the infections transmitted by other vectors, the age-distributions of the proportion of cases are entirely different. CONCLUSIONS: During specific outbreaks, the ratio between the age distribution of the proportion of officially reported cases and the total number of cases for Aedes transmitted infections such as dengue, chikungunya and zika is independent of the size of the outbreak, the size of the studied population, the period when the outbreak occurs; and the geographical region considered. Our results also suggest that the age-distribution of cases is mainly due to the interaction between vectors and their hosts.
title Age-dependent distribution of officially reported cases of vector-borne infections
topic Populations and Evolution
url https://arxiv.org/abs/2603.16773