A Novel end-to-end Digital Health System Using Deep Learning-based ECG Analysis

Fuente: arXiv
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Autori principali: Kontou, Artemis, Miroshnikova, Natalia, Matheou, Costakis, Sophocleous, Sophocles, Tsekouras, Nicholas, Malialis, Kleanthis, Kolios, Panayiotis
Natura: Preprint
Pubblicazione: 2026
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author Kontou, Artemis
Miroshnikova, Natalia
Matheou, Costakis
Sophocleous, Sophocles
Tsekouras, Nicholas
Malialis, Kleanthis
Kolios, Panayiotis
author_facet Kontou, Artemis
Miroshnikova, Natalia
Matheou, Costakis
Sophocleous, Sophocles
Tsekouras, Nicholas
Malialis, Kleanthis
Kolios, Panayiotis
contents This study presents AI-HEART, a cloud-based information system for managing and analysing long-duration ambulatory electrocardiogram (ECG) recordings and supporting clinician decision-making. The platform operationalises an end-to-end pipeline that ingests multi-day three-lead ECGs, normalises inputs, performs signal preprocessing, and applies dedicated deep neural networks for wave delineation, noise/quality detection, and beat- and rhythm-level multi-class arrhythmia classification. To address class imbalance and real-world signal variability, model development combines large clinically annotated datasets with expert-in-the-loop curation and generative augmentation for under-represented rhythms. Empirical evaluation on three-lead ambulatory ECG data shows that delineation accuracy is sufficient for automated interval measurement, noise detection reliably flags poor-quality segments, and arrhythmia classification achieves high specificity with clinically useful macro-averaged performance across common and rarer rhythms. Beyond predictive accuracy, AI-HEART provides a scalable deployment approach for integrating AI into routine ECG services, enabling traceable outputs, audit-friendly storage of recordings and derived annotations, and clinician review/editing that captures feedback for controlled model improvement. The findings demonstrate the technical feasibility and operational value of a noise-aware AI-ECG platform as a digital health information system.
format Preprint
id arxiv_https___arxiv_org_abs_2603_16891
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle A Novel end-to-end Digital Health System Using Deep Learning-based ECG Analysis
Kontou, Artemis
Miroshnikova, Natalia
Matheou, Costakis
Sophocleous, Sophocles
Tsekouras, Nicholas
Malialis, Kleanthis
Kolios, Panayiotis
Signal Processing
Artificial Intelligence
Human-Computer Interaction
Machine Learning
This study presents AI-HEART, a cloud-based information system for managing and analysing long-duration ambulatory electrocardiogram (ECG) recordings and supporting clinician decision-making. The platform operationalises an end-to-end pipeline that ingests multi-day three-lead ECGs, normalises inputs, performs signal preprocessing, and applies dedicated deep neural networks for wave delineation, noise/quality detection, and beat- and rhythm-level multi-class arrhythmia classification. To address class imbalance and real-world signal variability, model development combines large clinically annotated datasets with expert-in-the-loop curation and generative augmentation for under-represented rhythms. Empirical evaluation on three-lead ambulatory ECG data shows that delineation accuracy is sufficient for automated interval measurement, noise detection reliably flags poor-quality segments, and arrhythmia classification achieves high specificity with clinically useful macro-averaged performance across common and rarer rhythms. Beyond predictive accuracy, AI-HEART provides a scalable deployment approach for integrating AI into routine ECG services, enabling traceable outputs, audit-friendly storage of recordings and derived annotations, and clinician review/editing that captures feedback for controlled model improvement. The findings demonstrate the technical feasibility and operational value of a noise-aware AI-ECG platform as a digital health information system.
title A Novel end-to-end Digital Health System Using Deep Learning-based ECG Analysis
topic Signal Processing
Artificial Intelligence
Human-Computer Interaction
Machine Learning
url https://arxiv.org/abs/2603.16891