UNICORN: Ultrasound Nakagami Imaging via Score Matching and Adaptation for Assessing Hepatic Steatosis

Fuente: arXiv
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Autores principales: Kim, Kwanyoung, Lee, Jaa-Yeon, Ko, Youngjun, Lee, GunWoo, Ye, Jong Chul
Formato: Preprint
Publicado: 2026
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author Kim, Kwanyoung
Lee, Jaa-Yeon
Ko, Youngjun
Lee, GunWoo
Ye, Jong Chul
author_facet Kim, Kwanyoung
Lee, Jaa-Yeon
Ko, Youngjun
Lee, GunWoo
Ye, Jong Chul
contents Ultrasound imaging is an essential first-line tool for assessing hepatic steatosis. While conventional B-mode ultrasound imaging has limitations in providing detailed tissue characterization, ultrasound Nakagami imaging holds promise for visualizing and quantifying tissue scattering in backscattered signals, with potential applications in fat fraction analysis. However, existing methods for Nakagami imaging struggle with optimal window size selection and suffer from estimator instability, leading to degraded image resolution. To address these challenges, we propose a novel method called UNICORN (Ultrasound Nakagami Imaging via Score Matching and Adaptation), which offers an accurate, closed-form estimator for Nakagami parameter estimation based on the score function of the ultrasound envelope signal. Unlike methods that visualize only specific regions of interest (ROI) and estimate parameters within fixed window sizes, our approach provides comprehensive parameter mapping by providing a pixel-by-pixel estimator, resulting in high-resolution imaging. We demonstrated that our proposed estimator effectively assesses hepatic steatosis and provides visual distinction in the backscattered statistics associated with this condition. Through extensive experiments using real envelope data from patient, we validated that UNICORN enables clinical detection of hepatic steatosis and exhibits robustness and generalizability.
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id arxiv_https___arxiv_org_abs_2603_16942
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle UNICORN: Ultrasound Nakagami Imaging via Score Matching and Adaptation for Assessing Hepatic Steatosis
Kim, Kwanyoung
Lee, Jaa-Yeon
Ko, Youngjun
Lee, GunWoo
Ye, Jong Chul
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Quantitative Methods
Ultrasound imaging is an essential first-line tool for assessing hepatic steatosis. While conventional B-mode ultrasound imaging has limitations in providing detailed tissue characterization, ultrasound Nakagami imaging holds promise for visualizing and quantifying tissue scattering in backscattered signals, with potential applications in fat fraction analysis. However, existing methods for Nakagami imaging struggle with optimal window size selection and suffer from estimator instability, leading to degraded image resolution. To address these challenges, we propose a novel method called UNICORN (Ultrasound Nakagami Imaging via Score Matching and Adaptation), which offers an accurate, closed-form estimator for Nakagami parameter estimation based on the score function of the ultrasound envelope signal. Unlike methods that visualize only specific regions of interest (ROI) and estimate parameters within fixed window sizes, our approach provides comprehensive parameter mapping by providing a pixel-by-pixel estimator, resulting in high-resolution imaging. We demonstrated that our proposed estimator effectively assesses hepatic steatosis and provides visual distinction in the backscattered statistics associated with this condition. Through extensive experiments using real envelope data from patient, we validated that UNICORN enables clinical detection of hepatic steatosis and exhibits robustness and generalizability.
title UNICORN: Ultrasound Nakagami Imaging via Score Matching and Adaptation for Assessing Hepatic Steatosis
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Quantitative Methods
url https://arxiv.org/abs/2603.16942