Taming Epilepsy: Mean Field Control of Whole-Brain Dynamics
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arXiv
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| Autores principales: | , , |
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| Formato: | Preprint |
| Publicado: |
2026
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| _version_ | 1866912973514080256 |
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| author | Li, Ming Gao, Ting Dua, Jingqiao |
| author_facet | Li, Ming Gao, Ting Dua, Jingqiao |
| contents | Controlling the high-dimensional neural dynamics during epileptic seizures remains a significant challenge due to the nonlinear characteristics and complex connectivity of the brain. In this paper, we propose a novel framework, namely Graph-Regularized Koopman Mean-Field Game (GK-MFG), which integrates Reservoir Computing (RC) for Koopman operator approximation with Alternating Population and Agent Control Network (APAC-Net) for solving distributional control problems. By embedding Electroencephalogram (EEG) dynamics into a linear latent space and imposing graph Laplacian constraints derived from the Phase Locking Value (PLV), our method achieves robust seizure suppression while respecting the functional topological structure of the brain. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2603_18035 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Taming Epilepsy: Mean Field Control of Whole-Brain Dynamics Li, Ming Gao, Ting Dua, Jingqiao Machine Learning Controlling the high-dimensional neural dynamics during epileptic seizures remains a significant challenge due to the nonlinear characteristics and complex connectivity of the brain. In this paper, we propose a novel framework, namely Graph-Regularized Koopman Mean-Field Game (GK-MFG), which integrates Reservoir Computing (RC) for Koopman operator approximation with Alternating Population and Agent Control Network (APAC-Net) for solving distributional control problems. By embedding Electroencephalogram (EEG) dynamics into a linear latent space and imposing graph Laplacian constraints derived from the Phase Locking Value (PLV), our method achieves robust seizure suppression while respecting the functional topological structure of the brain. |
| title | Taming Epilepsy: Mean Field Control of Whole-Brain Dynamics |
| topic | Machine Learning |
| url | https://arxiv.org/abs/2603.18035 |