BSTModelKit.jl: A Julia Package for Constructing, Solving, and Analyzing Biochemical Systems Theory Models

Fuente: arXiv
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Hauptverfasser: Vadhin, Sandra, Varner, Jeffrey D.
Format: Preprint
Veröffentlicht: 2026
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author Vadhin, Sandra
Varner, Jeffrey D.
author_facet Vadhin, Sandra
Varner, Jeffrey D.
contents We present BSTModelKit.jl, an open-source Julia package for constructing, solving, and analyzing Biochemical Systems Theory (BST) models of biochemical networks. The package implements S-system representations, a canonical power-law formalism for modeling metabolic and regulatory networks. BSTModelKit.jl provides a declarative model specification format, dynamic simulation via ordinary differential equation (ODE) integration, steady-state computation, and global sensitivity analysis using the Morris and Sobol methods. The package leverages the Julia scientific computing ecosystem, in particular the SciML suite of differential equation solvers, to provide efficient and flexible model analysis tools. We describe the mathematical formulation, software design, and demonstrate the package capabilities with illustrative examples.
format Preprint
id arxiv_https___arxiv_org_abs_2603_19115
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle BSTModelKit.jl: A Julia Package for Constructing, Solving, and Analyzing Biochemical Systems Theory Models
Vadhin, Sandra
Varner, Jeffrey D.
Molecular Networks
Mathematical Software
We present BSTModelKit.jl, an open-source Julia package for constructing, solving, and analyzing Biochemical Systems Theory (BST) models of biochemical networks. The package implements S-system representations, a canonical power-law formalism for modeling metabolic and regulatory networks. BSTModelKit.jl provides a declarative model specification format, dynamic simulation via ordinary differential equation (ODE) integration, steady-state computation, and global sensitivity analysis using the Morris and Sobol methods. The package leverages the Julia scientific computing ecosystem, in particular the SciML suite of differential equation solvers, to provide efficient and flexible model analysis tools. We describe the mathematical formulation, software design, and demonstrate the package capabilities with illustrative examples.
title BSTModelKit.jl: A Julia Package for Constructing, Solving, and Analyzing Biochemical Systems Theory Models
topic Molecular Networks
Mathematical Software
url https://arxiv.org/abs/2603.19115