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| Main Authors: | , |
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| Format: | Preprint |
| Published: |
2026
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| Subjects: | |
| Online Access: | https://arxiv.org/abs/2603.19844 |
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| _version_ | 1866918410512760832 |
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| author | Kumar, Lokendra Aggarwal, Shubham |
| author_facet | Kumar, Lokendra Aggarwal, Shubham |
| contents | We present the first study of Hyper-Connections (HC) for volumetric multi-modal brain tumor segmentation, integrating them as a drop-in replacement for fixed residual connections across five architectures: nnU-Net, SwinUNETR, VT-UNet, U-Net, and U-Netpp. Dynamic HC consistently improves all 3D models on the BraTS 2021 dataset, yielding up to +1.03 percent mean Dice gain with negligible parameter overhead. Gains are most pronounced in the Enhancing Tumor sub-region, reflecting improved fine-grained boundary delineation. Modality ablation further reveals that HC-equipped models develop sharper sensitivity toward clinically dominant sequences, specifically T1ce for Tumor Core and Enhancing Tumor, and FLAIR for Whole Tumor, a behavior absent in fixed-connection baselines and consistent across all architectures. In 2D settings, improvements are smaller and configuration-sensitive, suggesting that volumetric spatial context amplifies the benefit of adaptive aggregation. These results establish HC as a simple, efficient, and broadly applicable mechanism for multi-modal feature fusion in medical image segmentation. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2603_19844 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Hyper-Connections for Adaptive Multi-Modal MRI Brain Tumor Segmentation Kumar, Lokendra Aggarwal, Shubham Computer Vision and Pattern Recognition We present the first study of Hyper-Connections (HC) for volumetric multi-modal brain tumor segmentation, integrating them as a drop-in replacement for fixed residual connections across five architectures: nnU-Net, SwinUNETR, VT-UNet, U-Net, and U-Netpp. Dynamic HC consistently improves all 3D models on the BraTS 2021 dataset, yielding up to +1.03 percent mean Dice gain with negligible parameter overhead. Gains are most pronounced in the Enhancing Tumor sub-region, reflecting improved fine-grained boundary delineation. Modality ablation further reveals that HC-equipped models develop sharper sensitivity toward clinically dominant sequences, specifically T1ce for Tumor Core and Enhancing Tumor, and FLAIR for Whole Tumor, a behavior absent in fixed-connection baselines and consistent across all architectures. In 2D settings, improvements are smaller and configuration-sensitive, suggesting that volumetric spatial context amplifies the benefit of adaptive aggregation. These results establish HC as a simple, efficient, and broadly applicable mechanism for multi-modal feature fusion in medical image segmentation. |
| title | Hyper-Connections for Adaptive Multi-Modal MRI Brain Tumor Segmentation |
| topic | Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2603.19844 |