Anatomical Token Uncertainty for Transformer-Guided Active MRI Acquisition
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arXiv
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| Autori principali: | , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2026
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| _version_ | 1866910081424031744 |
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| author | Ayzenberg, Lev Abu-Hussein, Shady Giryes, Raja Greenspan, Hayit |
| author_facet | Ayzenberg, Lev Abu-Hussein, Shady Giryes, Raja Greenspan, Hayit |
| contents | Full data acquisition in MRI is inherently slow, which limits clinical throughput and increases patient discomfort. Compressed Sensing MRI (CS-MRI) seeks to accelerate acquisition by reconstructing images from under-sampled k-space data, requiring both an optimal sampling trajectory and a high-fidelity reconstruction model. In this work, we propose a novel active sampling framework that leverages the inherent discrete structure of a pretrained medical image tokenizer and a latent transformer. By representing anatomy through a dictionary of quantized visual tokens, the model provides a well-defined probability distribution over the latent space. We utilize this distribution to derive a principled uncertainty measure via token entropy, which guides the active sampling process. We introduce two strategies to exploit this latent uncertainty: (1) Latent Entropy Selection (LES), projecting patch-wise token entropy into the $k$-space domain to identify informative sampling lines, and (2) Gradient-based Entropy Optimization (GEO), which identifies regions of maximum uncertainty reduction via the $k$-space gradient of a total latent entropy loss. We evaluate our framework on the fastMRI singlecoil Knee and Brain datasets at $\times 8$ and $\times 16$ acceleration. Our results demonstrate that our active policies outperform state-of-the-art baselines in perceptual metrics, and feature-based distances. Our code is available at https://github.com/levayz/TRUST-MRI. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2603_21806 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Anatomical Token Uncertainty for Transformer-Guided Active MRI Acquisition Ayzenberg, Lev Abu-Hussein, Shady Giryes, Raja Greenspan, Hayit Computer Vision and Pattern Recognition Full data acquisition in MRI is inherently slow, which limits clinical throughput and increases patient discomfort. Compressed Sensing MRI (CS-MRI) seeks to accelerate acquisition by reconstructing images from under-sampled k-space data, requiring both an optimal sampling trajectory and a high-fidelity reconstruction model. In this work, we propose a novel active sampling framework that leverages the inherent discrete structure of a pretrained medical image tokenizer and a latent transformer. By representing anatomy through a dictionary of quantized visual tokens, the model provides a well-defined probability distribution over the latent space. We utilize this distribution to derive a principled uncertainty measure via token entropy, which guides the active sampling process. We introduce two strategies to exploit this latent uncertainty: (1) Latent Entropy Selection (LES), projecting patch-wise token entropy into the $k$-space domain to identify informative sampling lines, and (2) Gradient-based Entropy Optimization (GEO), which identifies regions of maximum uncertainty reduction via the $k$-space gradient of a total latent entropy loss. We evaluate our framework on the fastMRI singlecoil Knee and Brain datasets at $\times 8$ and $\times 16$ acceleration. Our results demonstrate that our active policies outperform state-of-the-art baselines in perceptual metrics, and feature-based distances. Our code is available at https://github.com/levayz/TRUST-MRI. |
| title | Anatomical Token Uncertainty for Transformer-Guided Active MRI Acquisition |
| topic | Computer Vision and Pattern Recognition |
| url | https://arxiv.org/abs/2603.21806 |