Invariant ionic conductance in an atomically thin polar nanopore

Fuente: arXiv
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Main Authors: Zhang, Shengping, Zeng, Haiou, Wu, Ningran, Xue, Guodong, Li, Xiao, Saxena, Anshul, Tong, Junhe, Liang, Nianjie, Zhuang, Zeyu, Yang, Jing, Aluru, Narayana R., Liu, Kaihui, Song, Bai, Wang, Luda
Format: Preprint
Published: 2026
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author Zhang, Shengping
Zeng, Haiou
Wu, Ningran
Xue, Guodong
Li, Xiao
Saxena, Anshul
Tong, Junhe
Liang, Nianjie
Zhuang, Zeyu
Yang, Jing
Aluru, Narayana R.
Liu, Kaihui
Song, Bai
Wang, Luda
author_facet Zhang, Shengping
Zeng, Haiou
Wu, Ningran
Xue, Guodong
Li, Xiao
Saxena, Anshul
Tong, Junhe
Liang, Nianjie
Zhuang, Zeyu
Yang, Jing
Aluru, Narayana R.
Liu, Kaihui
Song, Bai
Wang, Luda
contents Ion channels regulate many essential properties of biological cells, especially the membrane potential. Despite decades of efforts on artificial channels, it remains a great challenge to mimic the dipole potential-an indispensable constituent of the membrane potential, due to its angstrom-scale characteristic length. Here, we explore nanopores in monolayer molybdenum sulfide selenide (MoSSe) considering its intrinsic dipole and atomic thickness. Remarkably, an invariant ionic conductance was observed over salt concentrations spanning six orders of magnitude, distinct from all known conductance-concentration scaling laws and reminiscent of the current saturation in cell membranes at high concentrations. Molecular dynamics simulations revealed the fundamental role of the dipole-modulated dielectric properties of nanoconfined water. Our findings highlight an exotic conductance scaling law and open up a novel avenue for controlling ion transport in unprecedented ways.
format Preprint
id arxiv_https___arxiv_org_abs_2603_21827
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Invariant ionic conductance in an atomically thin polar nanopore
Zhang, Shengping
Zeng, Haiou
Wu, Ningran
Xue, Guodong
Li, Xiao
Saxena, Anshul
Tong, Junhe
Liang, Nianjie
Zhuang, Zeyu
Yang, Jing
Aluru, Narayana R.
Liu, Kaihui
Song, Bai
Wang, Luda
Mesoscale and Nanoscale Physics
Ion channels regulate many essential properties of biological cells, especially the membrane potential. Despite decades of efforts on artificial channels, it remains a great challenge to mimic the dipole potential-an indispensable constituent of the membrane potential, due to its angstrom-scale characteristic length. Here, we explore nanopores in monolayer molybdenum sulfide selenide (MoSSe) considering its intrinsic dipole and atomic thickness. Remarkably, an invariant ionic conductance was observed over salt concentrations spanning six orders of magnitude, distinct from all known conductance-concentration scaling laws and reminiscent of the current saturation in cell membranes at high concentrations. Molecular dynamics simulations revealed the fundamental role of the dipole-modulated dielectric properties of nanoconfined water. Our findings highlight an exotic conductance scaling law and open up a novel avenue for controlling ion transport in unprecedented ways.
title Invariant ionic conductance in an atomically thin polar nanopore
topic Mesoscale and Nanoscale Physics
url https://arxiv.org/abs/2603.21827