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Main Authors: Han, Xiao, Fan, Yuzheng, Zhao, Sendong, Wang, Haochun, Qin, Bing
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2603.22096
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author Han, Xiao
Fan, Yuzheng
Zhao, Sendong
Wang, Haochun
Qin, Bing
author_facet Han, Xiao
Fan, Yuzheng
Zhao, Sendong
Wang, Haochun
Qin, Bing
contents Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval, unreliable reuse, and in some cases even hurt performance compared to direct LLM inference. We propose GSEM (Graph-based Self-Evolving Memory), a clinical memory framework that organizes clinical experiences into a dual-layer memory graph, capturing both the decision structure within each experience and the relational dependencies across experiences, and supporting applicability-aware retrieval and online feedback-driven calibration of node quality and edge weights. Across MedR-Bench and MedAgentsBench with two LLM backbones, GSEM achieves the highest average accuracy among all baselines, reaching 70.90\% and 69.24\% with DeepSeek-V3.2 and Qwen3.5-35B, respectively. Code is available at https://github.com/xhan1022/gsem.
format Preprint
id arxiv_https___arxiv_org_abs_2603_22096
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle GSEM: Graph-based Self-Evolving Memory for Experience Augmented Clinical Reasoning
Han, Xiao
Fan, Yuzheng
Zhao, Sendong
Wang, Haochun
Qin, Bing
Artificial Intelligence
Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval, unreliable reuse, and in some cases even hurt performance compared to direct LLM inference. We propose GSEM (Graph-based Self-Evolving Memory), a clinical memory framework that organizes clinical experiences into a dual-layer memory graph, capturing both the decision structure within each experience and the relational dependencies across experiences, and supporting applicability-aware retrieval and online feedback-driven calibration of node quality and edge weights. Across MedR-Bench and MedAgentsBench with two LLM backbones, GSEM achieves the highest average accuracy among all baselines, reaching 70.90\% and 69.24\% with DeepSeek-V3.2 and Qwen3.5-35B, respectively. Code is available at https://github.com/xhan1022/gsem.
title GSEM: Graph-based Self-Evolving Memory for Experience Augmented Clinical Reasoning
topic Artificial Intelligence
url https://arxiv.org/abs/2603.22096