When Models Learn to Ask Why: Adaptive Causal Reasoning for Trustworthy Medical Vision-Language Models

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Auteurs principaux: Lin, Jianxin, Zhu, Chunzheng, Kneuertz, Peter J., Bai, Yunfei, Xue, Yuan
Format: Preprint
Publié: 2026
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author Lin, Jianxin
Zhu, Chunzheng
Kneuertz, Peter J.
Bai, Yunfei
Xue, Yuan
author_facet Lin, Jianxin
Zhu, Chunzheng
Kneuertz, Peter J.
Bai, Yunfei
Xue, Yuan
contents Vision-Language Models (VLMs) have enabled interpretable medical diagnosis by integrating visual perception with linguistic reasoning. Yet, existing medical chain-of-thought (CoT) models lack explicit mechanisms to represent and enforce causal reasoning, leaving them vulnerable to spurious correlations and limiting their clinical reliability. We pinpoint three core challenges in medical CoT reasoning: how to adaptively trigger causal correction, construct high-quality causal-spurious contrastive samples, and maintain causal consistency across reasoning trajectories. To address these challenges, we propose MedCausalX, an end-to-end framework explicitly models causal reasoning chains in medical VLMs. We first introduce the CRMed dataset providing fine-grained anatomical annotations, structured causal reasoning chains, and counterfactual variants that guide the learning of causal relationships beyond superficial correlations. Building upon CRMed, MedCausalX employs a two-stage adaptive reflection architecture equipped with $\langle$causal$\rangle$ and $\langle$verify$\rangle$ tokens, enabling the model to autonomously determine when and how to perform causal analysis and verification. Finally, a trajectory-level causal correction objective optimized through error-attributed reinforcement learning refines the reasoning chain, allowing the model to distinguish genuine causal dependencies from shortcut associations. Extensive experiments on multiple benchmarks show that MedCausalX consistently outperforms state-of-the-art methods, improving diagnostic consistency by +5.4 points, reducing hallucination by over 10 points, and attaining top spatial grounding IoU, thereby setting a new standard for causally grounded medical reasoning. The code and dataset are available at https://github.com/zhcz328/MedCausalX.
format Preprint
id arxiv_https___arxiv_org_abs_2603_23085
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle When Models Learn to Ask Why: Adaptive Causal Reasoning for Trustworthy Medical Vision-Language Models
Lin, Jianxin
Zhu, Chunzheng
Kneuertz, Peter J.
Bai, Yunfei
Xue, Yuan
Artificial Intelligence
Vision-Language Models (VLMs) have enabled interpretable medical diagnosis by integrating visual perception with linguistic reasoning. Yet, existing medical chain-of-thought (CoT) models lack explicit mechanisms to represent and enforce causal reasoning, leaving them vulnerable to spurious correlations and limiting their clinical reliability. We pinpoint three core challenges in medical CoT reasoning: how to adaptively trigger causal correction, construct high-quality causal-spurious contrastive samples, and maintain causal consistency across reasoning trajectories. To address these challenges, we propose MedCausalX, an end-to-end framework explicitly models causal reasoning chains in medical VLMs. We first introduce the CRMed dataset providing fine-grained anatomical annotations, structured causal reasoning chains, and counterfactual variants that guide the learning of causal relationships beyond superficial correlations. Building upon CRMed, MedCausalX employs a two-stage adaptive reflection architecture equipped with $\langle$causal$\rangle$ and $\langle$verify$\rangle$ tokens, enabling the model to autonomously determine when and how to perform causal analysis and verification. Finally, a trajectory-level causal correction objective optimized through error-attributed reinforcement learning refines the reasoning chain, allowing the model to distinguish genuine causal dependencies from shortcut associations. Extensive experiments on multiple benchmarks show that MedCausalX consistently outperforms state-of-the-art methods, improving diagnostic consistency by +5.4 points, reducing hallucination by over 10 points, and attaining top spatial grounding IoU, thereby setting a new standard for causally grounded medical reasoning. The code and dataset are available at https://github.com/zhcz328/MedCausalX.
title When Models Learn to Ask Why: Adaptive Causal Reasoning for Trustworthy Medical Vision-Language Models
topic Artificial Intelligence
url https://arxiv.org/abs/2603.23085