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Main Authors: Kim, Hyunwoo, Kim, Heesuk, Choi, Wungrak, Hyun, Jae-Sang
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2603.24115
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author Kim, Hyunwoo
Kim, Heesuk
Choi, Wungrak
Hyun, Jae-Sang
author_facet Kim, Hyunwoo
Kim, Heesuk
Choi, Wungrak
Hyun, Jae-Sang
contents For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual information across adjacent B-scans. 3D segmentation methods are better for capturing slice-to-slice context, but they require expensive computational resources. To address these limitations, we propose a 2.5D segmentation framework that incorporates a novel cross-slice feature fusion (CFF) module into a U-Net-like architecture. The CFF module fuses inter-slice features to effectively capture contextual information, enabling consistent boundary detection across slices and improved robustness in noisy regions. The framework was validated on both a clinical dataset and the publicly available DUKE DME dataset. Compared to other segmentation methods without the CFF module, the proposed method achieved an 8.56% reduction in mean absolute distance and a 13.92% reduction in root mean square error, demonstrating improved segmentation accuracy and robustness. Overall, the proposed 2.5D framework balances contextual awareness and computational efficiency, enabling anatomically reliable retinal layer delineation for automated glaucoma evaluation and potential clinical applications.
format Preprint
id arxiv_https___arxiv_org_abs_2603_24115
institution arXiv
publishDate 2026
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spellingShingle Retinal Layer Segmentation in OCT Images With 2.5D Cross-slice Feature Fusion Module for Glaucoma Assessment
Kim, Hyunwoo
Kim, Heesuk
Choi, Wungrak
Hyun, Jae-Sang
Computer Vision and Pattern Recognition
For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual information across adjacent B-scans. 3D segmentation methods are better for capturing slice-to-slice context, but they require expensive computational resources. To address these limitations, we propose a 2.5D segmentation framework that incorporates a novel cross-slice feature fusion (CFF) module into a U-Net-like architecture. The CFF module fuses inter-slice features to effectively capture contextual information, enabling consistent boundary detection across slices and improved robustness in noisy regions. The framework was validated on both a clinical dataset and the publicly available DUKE DME dataset. Compared to other segmentation methods without the CFF module, the proposed method achieved an 8.56% reduction in mean absolute distance and a 13.92% reduction in root mean square error, demonstrating improved segmentation accuracy and robustness. Overall, the proposed 2.5D framework balances contextual awareness and computational efficiency, enabling anatomically reliable retinal layer delineation for automated glaucoma evaluation and potential clinical applications.
title Retinal Layer Segmentation in OCT Images With 2.5D Cross-slice Feature Fusion Module for Glaucoma Assessment
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2603.24115