Saved in:
Bibliographic Details
Main Authors: Li, Harrison, Wang, Kevin, Cho, Cheol Jun, Lian, Jiachen, Rangwala, Rabab, Guo, Chenxu, Yang, Emma, Kurteff, Lynn, Ezzes, Zoe, Keegan-Rodewald, Willa, Vonk, Jet, Ramkrishnan, Siddarth, Antonicelli, Giada, Miller, Zachary, Tempini, Marilu Gorno, Anumanchipalli, Gopala
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2603.26795
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866914427182252032
author Li, Harrison
Wang, Kevin
Cho, Cheol Jun
Lian, Jiachen
Rangwala, Rabab
Guo, Chenxu
Yang, Emma
Kurteff, Lynn
Ezzes, Zoe
Keegan-Rodewald, Willa
Vonk, Jet
Ramkrishnan, Siddarth
Antonicelli, Giada
Miller, Zachary
Tempini, Marilu Gorno
Anumanchipalli, Gopala
author_facet Li, Harrison
Wang, Kevin
Cho, Cheol Jun
Lian, Jiachen
Rangwala, Rabab
Guo, Chenxu
Yang, Emma
Kurteff, Lynn
Ezzes, Zoe
Keegan-Rodewald, Willa
Vonk, Jet
Ramkrishnan, Siddarth
Antonicelli, Giada
Miller, Zachary
Tempini, Marilu Gorno
Anumanchipalli, Gopala
contents Building a diagnosis model for primary progressive aphasia (PPA) has been challenging due to the data scarcity. Collecting clinical data at scale is limited by the high vulnerability of clinical population and the high cost of expert labeling. To circumvent this, previous studies simulate dysfluent speech to generate training data. However, those approaches are not comprehensive enough to simulate PPA as holistic, multi-level phenotypes, instead relying on isolated dysfluencies. To address this, we propose a novel, clinically grounded simulation framework, Hierarchical Aphasic Speech Simulation (HASS). HASS aims to simulate behaviors of logopenic variant of PPA (lvPPA) with varying degrees of severity. To this end, semantic, phonological, and temporal deficits of lvPPA are systematically identified by clinical experts, and simulated. We demonstrate that our framework enables more accurate and generalizable detection models.
format Preprint
id arxiv_https___arxiv_org_abs_2603_26795
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle HASS: Hierarchical Simulation of Logopenic Aphasic Speech for Scalable PPA Detection
Li, Harrison
Wang, Kevin
Cho, Cheol Jun
Lian, Jiachen
Rangwala, Rabab
Guo, Chenxu
Yang, Emma
Kurteff, Lynn
Ezzes, Zoe
Keegan-Rodewald, Willa
Vonk, Jet
Ramkrishnan, Siddarth
Antonicelli, Giada
Miller, Zachary
Tempini, Marilu Gorno
Anumanchipalli, Gopala
Audio and Speech Processing
Artificial Intelligence
Sound
Building a diagnosis model for primary progressive aphasia (PPA) has been challenging due to the data scarcity. Collecting clinical data at scale is limited by the high vulnerability of clinical population and the high cost of expert labeling. To circumvent this, previous studies simulate dysfluent speech to generate training data. However, those approaches are not comprehensive enough to simulate PPA as holistic, multi-level phenotypes, instead relying on isolated dysfluencies. To address this, we propose a novel, clinically grounded simulation framework, Hierarchical Aphasic Speech Simulation (HASS). HASS aims to simulate behaviors of logopenic variant of PPA (lvPPA) with varying degrees of severity. To this end, semantic, phonological, and temporal deficits of lvPPA are systematically identified by clinical experts, and simulated. We demonstrate that our framework enables more accurate and generalizable detection models.
title HASS: Hierarchical Simulation of Logopenic Aphasic Speech for Scalable PPA Detection
topic Audio and Speech Processing
Artificial Intelligence
Sound
url https://arxiv.org/abs/2603.26795