Better than Average: Spatially-Aware Aggregation of Segmentation Uncertainty Improves Downstream Performance

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Auteurs principaux: Guarino, Vanessa Emanuela, Winklmayr, Claudia, Franzen, Jannik, Rumberger, Josef Lorenz, Pfeuffer, Manuel, Greven, Sonja, Maier-Hein, Klaus, Lüth, Carsten T., Karg, Christoph, Kainmueller, Dagmar
Format: Preprint
Publié: 2026
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author Guarino, Vanessa Emanuela
Winklmayr, Claudia
Franzen, Jannik
Rumberger, Josef Lorenz
Pfeuffer, Manuel
Greven, Sonja
Maier-Hein, Klaus
Lüth, Carsten T.
Karg, Christoph
Kainmueller, Dagmar
author_facet Guarino, Vanessa Emanuela
Winklmayr, Claudia
Franzen, Jannik
Rumberger, Josef Lorenz
Pfeuffer, Manuel
Greven, Sonja
Maier-Hein, Klaus
Lüth, Carsten T.
Karg, Christoph
Kainmueller, Dagmar
contents Uncertainty Quantification (UQ) is crucial for ensuring the reliability of automated image segmentations in safety-critical domains like biomedical image analysis or autonomous driving. In segmentation, UQ generates pixel-wise uncertainty scores that must be aggregated into image-level scores for downstream tasks like Out-of-Distribution (OoD) or failure detection. Despite routine use of aggregation strategies, their properties and impact on downstream task performance have not yet been comprehensively studied. Global Average is the default choice, yet it does not account for spatial and structural features of segmentation uncertainty. Alternatives like patch-, class- and threshold-based strategies exist, but lack systematic comparison, leading to inconsistent reporting and unclear best practices. We address this gap by (1) formally analyzing properties, limitations, and pitfalls of common strategies; (2) proposing novel strategies that incorporate spatial uncertainty structure and (3) benchmarking their performance on OoD and failure detection across ten datasets that vary in image geometry and structure. We find that aggregators leveraging spatial structure yield stronger performance in both downstream tasks studied. However, the performance of individual aggregators depends heavily on dataset characteristics, so we (4) propose a meta-aggregator that integrates multiple aggregators and performs robustly across datasets.
format Preprint
id arxiv_https___arxiv_org_abs_2603_29941
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Better than Average: Spatially-Aware Aggregation of Segmentation Uncertainty Improves Downstream Performance
Guarino, Vanessa Emanuela
Winklmayr, Claudia
Franzen, Jannik
Rumberger, Josef Lorenz
Pfeuffer, Manuel
Greven, Sonja
Maier-Hein, Klaus
Lüth, Carsten T.
Karg, Christoph
Kainmueller, Dagmar
Computer Vision and Pattern Recognition
Machine Learning
Uncertainty Quantification (UQ) is crucial for ensuring the reliability of automated image segmentations in safety-critical domains like biomedical image analysis or autonomous driving. In segmentation, UQ generates pixel-wise uncertainty scores that must be aggregated into image-level scores for downstream tasks like Out-of-Distribution (OoD) or failure detection. Despite routine use of aggregation strategies, their properties and impact on downstream task performance have not yet been comprehensively studied. Global Average is the default choice, yet it does not account for spatial and structural features of segmentation uncertainty. Alternatives like patch-, class- and threshold-based strategies exist, but lack systematic comparison, leading to inconsistent reporting and unclear best practices. We address this gap by (1) formally analyzing properties, limitations, and pitfalls of common strategies; (2) proposing novel strategies that incorporate spatial uncertainty structure and (3) benchmarking their performance on OoD and failure detection across ten datasets that vary in image geometry and structure. We find that aggregators leveraging spatial structure yield stronger performance in both downstream tasks studied. However, the performance of individual aggregators depends heavily on dataset characteristics, so we (4) propose a meta-aggregator that integrates multiple aggregators and performs robustly across datasets.
title Better than Average: Spatially-Aware Aggregation of Segmentation Uncertainty Improves Downstream Performance
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2603.29941